Wound Healing, Fibrosis, and the Myofibroblast
A Historical and Biological Perspective

Explores how the concept of fibrosis was generated, how it evolved during the story of medicine, and its links to modern research and medicine

Giulio Gabbiani (Author), Matteo Coen (Author), Fabio Zampieri (Author)

9780323905466, Elsevier Science

Paperback / softback, published 30 September 2021

132 pages
22.9 x 15.2 x 1 cm, 0.23 kg

Wound Healing, and the Myofibroblast: A Historical and Biological Perspective is the fruit of an interdisciplinary and international collaboration involving a historian of medicine (Dr. Zampieri), a physician (Dr. Coen), and a researcher (Prof. Gabbiani, world-renowned for his discovery of the myofibroblast). This book aims to draw a concise yet complete description of the conceptual evolution of wound healing, fibrosis and fibrosis-related pathologies from antiquity to present time, as well as commenting on the role of the myofibroblast and the key cell type essential for tissue repair and fibrosis (from its identification in 1971 throughout its 50-years-old history).

By viewing this complex and century-long history from different perspectives, the book's authors aim to draw an exhaustive overview, with the hope of inspiring new and fruitful basic and clinical research.

1. Introduction
2. Fibrous Tissue, Fibrosis and the Fibroblast
3. Wound healing and Wound Contraction
4. Fibrotic Diseases
5. The Myofibroblast: Role in Fibrosis Development
6. Conclusions and Perspectives
7. Bibliography

Subject Areas: Life sciences: general issues [PSA]