Freshly Printed - allow 7 days lead
Couldn't load pickup availability
When Cells Die II
A Comprehensive Evaluation of Apoptosis and Programmed Cell Death
Richard A. Lockshin (Edited by), RA Lockshin (Author), Zahra Zakeri (Edited by)
9780471219477, Wiley
Hardback, published 20 January 2004
580 pages, Photos: 7 B&W, 4 Color; Drawings: 57 B&W, 0 Color; Tables: 11 B&W, 0 Color
24.4 x 16.2 x 3.1 cm, 0.924 kg
"...thoughtfully edited and readable. The book illustrates the importance of apoptosis in development, homeostasis, and human disease...an important contribution to the literature." (Doody's Book Review Service) "…thoroughly researched, highly readable, and informative." (E-STREAMS, March 2005)
Cell death is fast becoming one of the most dynamic areas of biological research-involving as it does the study of apoptosis and programmed cell death and the role these phenomena play in development and homeostasis on the one hand, and aging and disease on the other. The profound implications for medicine and agriculture from the manipulation of these processes have spawned a deluge of research papers, articles, approaches, and methods-making it difficult for scientists to get an overview of the field.
When Cells Die II: A Comprehensive Evaluation of Apoptosis and Programmed Cell Death offers the most thorough, cutting-edge coverage of this field since publication of the acclaimed first edition. Leading international researchers present an up-to-date yet accessible survey ranging from the history of cell death science to its modern methodology. Extensively revised to include major advances in research, this new edition features relevant discussion of:
* The impact of genomics and proteomics
* Gene therapy and pharmacogenetics
* The role of mitochondria
* Caspase-independent and non-apoptotic cell death
* Evolution of mechanisms
With the manipulation of programmed cell death in clinical situations now in the foreseeable future, When Cells Die II also addresses the role of apoptosis in specific organ systems-the immune system, nervous system, and gastrointestinal tract-as well as different disease states, including viral infection, cancer, and myocardial infarct.
Expertly edited to provide detailed cross-referencing, consistency of style, and a logical progression of topics, When Cells Die II is the definitive resource for understanding current cell death science. It will prove an invaluable text for advanced undergraduate, graduate, and medical students, postdoctoral fellows, scientists, and clinicians in cell biology, immunology, developmental biology, neuroscience, and cancer research.
Contributors vii Preface xi Section I Cell Death Origin and Progression 1 Introduction 3 Section II Biological Role of Cell Death in Development and Homeostasis 2 Cell Death: Shaping an Embryo 27 3 Cell Death in Dictyostelium: Assessing a Genetic Approach 59 4 Programmed Cell Death in Drosophila Melanogaster 79 5 Cell Death in Plant Development and Defense 99 6 Regulation of Apoptosis by Extracellular Matrix During Postembryonic Development in Xenopus Laevis 123 7 Apoptosis in the Immune System 143 8 Cell Death in Neuronal Development and Maintenance 175 9 Cell Turnover: Intestine and other Tissues 201 10 Cell Death, Aging Phenotypes, and Models of Premature Aging 241 Section III How Cell Death Is Carried Out 11 Survival Factors 257 12 Caspase-independent and Autophagic Programmed Cell Death 275 13 The Recognition and Engulfment of Apoptotic Cells by Phagocytes 311 14 Cell Cycle Genes: pRb and P53 339 15 Mitochondria and Oxidation in the Regulation of Cell Death 381 Section IV Deregulation of Cell Death in Disease and Future Intervention 16 the Use of Proteomics to Identify and Characterize Cell Death Proteins 405 17 Cell Death in Viral Infections, 435 18 Cell Death in Cancer and Cancer Therapy 461 19 the Role of Apoptosis in Myocardial Infarction and Heart Failure 483 Index 521
Richard A. Lockshin and Zahra Zakeri
Zahra Zakeri and Richard A. Lockshin
Jean-Pierre Levraud, Myriam Adam, Marie-Françoise Luciani, Laurence Aubry, Gérard Klein, and Pierre Golstein
Loretta Dorstyn and Sharad Kumar
Ron Mittler and Alice Y. Cheung
Atsuko Ishizuya-Oka, Tosikazu Amano, Liezhen Fu, and Yun-Bo Shi
Alexandra Brás, David García-Domingo, and Carlos Martinez-A.
Aviva M. Tolkovsky, Edward T. W. Bampton, and Cristoph G. Goemans
James W. Wilson and Christopher S. Potten
Huber R. Warner
David L. Vaux
Wilfried Bursch, Adolf Ellinger, Christopher Gerner, and Rolf Schulte-Hermann
Raymond B. Birge
Nianli Sang and Antonio Giordano
John D. Robertson, Sten Orrenius, and Boris Zhivotovsky
Xavier Saelens, Geert van Loo, Kris Gevaert, Joel Vanderkerckhove, and Peter Vandenabeele
Ying-bei Chen, Yihru Fannjiang, and J. Marie Hardwick
Simone Fulda and Klaus-Michael Debatin
Kartik Mani, Chang-Fu Peng, Gregg Rosner, and Richard N. Kitsis
Subject Areas: Biology, life sciences [PS]
