Volvox
A Search for the Molecular and Genetic Origins of Multicellularity and Cellular Differentiation

This book reviews Volvox development and biology and, through this study, sheds light on the origins of multicellularity.

David L. Kirk (Author)

9780521019149, Cambridge University Press

Paperback, published 8 September 2005

400 pages, 77 b/w illus. 10 tables
22.9 x 15.3 x 2.4 cm, 0.607 kg

'In this excellent, well-written and well-documented monograph, Kirk has made a critical compilation of the accumulated literature on Volvox and has encompassed the whole field, the pinnacle of which is his own work.' Lothar Jaenicke, Trends in Microbiology

The central thesis of this book is that Volvox and its unicellular and colonial relatives provide a wholly unrivalled opportunity to explore the proximate and ultimate causes underlying the evolution, from unicellular ancestors, of multicellular organisms with fully differentiated cell types. A major portion of the book is devoted to reviewing what is known about the genetic, cellular and molecular basis of development in the most extensively studied species of Volvox: V. cateri, which exhibits a complete division of labour between mortal somatic cells and immortal germ cells. However, this topic has been put in context by first considering the ecological conditions and cytological preconditions that appear to have fostered the evolution of organisms of progressively increasing size and with progressively increasing tendency to produce terminally differentiated somatic cells. The book concludes by raising the question of whether the germensoma dichotomy may have evolved by similar or different genetic pathways in different species of Volvox. Biologists and phycologists interested in development, genetics and cellular evolution will find this a fascinating work.

Prologue
1. Introduction
2. The volvocales: many cellular innovations
3. Ecological factors fostering the evolution of Volvox
4. Cytological features fostering the evolution of Volvox
5. Volvox V. Carteri: a Rosetta stone for deciphering the origins of cytodifferentiation
6. Mutational analysis of the V. Carteri development program
7. Molecular analysis of V. Carteri genes and development
Epilogue
References.

Subject Areas: Botany & plant sciences [PST], Developmental biology [PSC], Genetics [non-medical PSAK]