Understanding Pathogen Behaviour
Virulence, Stress Response and Resistance

M. Griffiths (Edited by)

9781855739536, Elsevier Science

Hardback, published 30 July 2005

624 pages
23.3 x 15.6 x 3.4 cm, 1.06 kg

"…an essential resource for all in the food safety industry. …a must-have microbiology text, dealing with prevailing issues in the food safety industry worldwide." --Food Processing

"…a well written book containing a wealth of up-to-date information." --Microbiology Today 2006

"…highly recommended to food scientists and, especially, to practical workers in the food industry, who are responsible for ensuring food safety." --Advances in Food Science

Pathogens respond dynamically to their environment. Understanding their behaviour is critical both because of evidence of increased resistance to established sanitation and preservation techniques, and because of the increased use of minimal processing technologies which are more vulnerable to the development of resistance. Understanding pathogen behaviour summarises the wealth of recent research and its implications for the food industry.

After two introductory chapters on ways of analysing and modelling pathogens, Part one summarises current research on what determines pathogenicity, stress response, adaptation and resistance. Part two reviews the behaviour of particular pathogens, reviewing virulence, stress response and resistance mechanisms in such pathogens as Salmonella, E.coli and Campylobacter. The final part of the book assesses how pathogens react and adapt to particular stresses from heat treatment and the effects of low temperature to the use of disinfectants and sanitisers.

With its distinguished editor and international team of contributors, Understanding pathogen behaviour is a standard reference for the food industry in ensuring food safety.

Part 1 Understanding virulence, stress response and resistance mechanisms: Understanding the behaviour of pathogenic cells: Proteome and metabolome analysis
Mechanistic modelling of pathogen stress response
The development of pathogenicity
Host–pathogen interactions
Factors affecting stress response
Cross-protective effects of bacterial stress
Sublethal injury, pathogen virulence and adaptation
Detecting sublethally-damaged cells. Part 2 Virulence and stress response mechanisms of particular pathogens: Salmonella: Virulence, stress response and resistance
E.coli: Virulence, stress response and resistance
Campylobacter: Stress response and resistance
Bacillus cereus: Factors affecting virulence
Staphylococcus aureus: Pathogenesis and stress response
Vibrio species: Pathogenesis and stress response. Part 3 Pathogen resistance and adaptation to particular stresses: Understanding pathogen survival and resistance in the food chain
Pathogen resistance and adaptation to heat stress
Pathogen resistance and adaptation to emerging technologies
Pathogen resistance and adaptation to natural antimicrobials
Pathogen resistance and adaptation to disinfectants and sanitisers
Pathogen resistance and adaptation to low temperature. Part 4 Appendix: Clostridium
Quorum sensing.

Subject Areas: Food & beverage technology [TDCT]