Transgenic Plants
A Production System for Industrial and Pharmaceutical Proteins

Meran R. L. Owen (Edited by), MRL Owen (Author), Jan Pen (Edited by)

9780471964438, Wiley

Hardback, published 20 November 1996

364 pages
25 x 17.9 x 2.6 cm, 0.794 kg

Transgenic Plants: A Production System for Industrial andPharmaceutical Proteins provides a detailed guide to the principlesand practice of using transgenic plants as a system for theproduction of heterologous proteins. It is unique in that it coversthe complete process of heterologous protein production in plants,from the initial transformation of the plant, through totranscription, transgene stability and finally the downstreamingprocessing events for protein purification. Written by aninternational team of industrialists and academics, this bookdescribes:
* the fundamental issues associated with expressing heterologousproteins in plants;
* a number of detailed examples of the successful small-andlarge-scale production of proteins;
* the essentials of patenting; and
* the commercial exploitation.
Transgenic Plants: A Production System for Industrial andPharmaceutical Proteins will be of interest to plantbiotechnologists, molecular biologists and protein biochemists inthe biotechnology and pharmaceutical industries.

Partial table of contents:

FUNDAMENTAL ASPECTS IN THE PRODUCTION OF RECOMBINANT PROTEINS INPLANTS.

Expression in Plants.

The Production of Recombinant Glycoproteins with DefinedNon-Immunogenic Glycans.

Downstream Processing of Proteins from Transgenic Plants.

Comparison of Host Systems for the Production of RecombinantProteins.

Transgene Stability.

EXAMPLES.

Industrial Enzymes.

Pharmaceutical Proteins.

COMMERCIALIZATION.

Patents and Biotechnology.

Commercialization of Phytase-Containing Seed.

Index.

Subject Areas: Biology, life sciences [PS]