Toxoplasmosis
A Comprehensive Clinical Guide

This authoritative account looks at the re-emergence of toxoplasmosis as a significant and potentially fatal infection.

David H. M. Joynson (Edited by), Tim G. Wreghitt (Edited by)

9780521019422, Cambridge University Press

Paperback, published 8 September 2005

412 pages, 37 b/w illus. 43 tables
25.5 x 17.8 x 2.4 cm, 0.996 kg

'I recommend this volume to microbiologists and epidemiologists, as well as to clinicians of different specialities, such as primary care physicians, gynaecologists, and paediatricians both in practice and in training, and all those who care for patients affected by T. gondii.' The Lancet

This authoritative and comprehensive account looks at the re-emergence of toxoplasmosis as a significant and potentially fatal infection. A team of acknowledged international experts review the latest diagnostic techniques, and the management of infection in pregnant women, neonates, the eye, transplant and other immunosuppressed patients and those with AIDS. The contentious issue of the role of screening during pregnancy and in the new-born is covered in depth. The introductory chapters on biology, immunology and epidemiology of the infection provide essential background to understanding the clinical disease. The full range of treatment strategies are presented in an easily accessible form. The natural history and life cycle of the causative organism, Toxoplasma gondii, provide a fascinating insight into one of the most successful parasites on earth. Although the burden of this disease varies greatly from country to country, it remains a global public health problem which affects about one billion individuals.

Preface
Historical perspective
1. Biology Eskild Petersen and J. P. Dubey
2. Immunology of toxoplasma infection Christopher A. Hunter and Gabrielle Reichman
3. Epidemiology Susan M. Hall, Michael Ryan and David Buxton
4. Infection in the immunocompetent Darrel O. Ho-Yen
5. Infections in HIV positive patients Peter Mariuz and Roy T. Steigbigel
6. Infection in other immunosuppressed patients Tim G. Wreghitt and David H. M. Joynson
7. Maternal and fetal infection Philippe Thulliez
8. Prenatal screening Ruth Gilbert and Catherine S. Peckham
9. Newborn screening Roger Eaton, George F. Grady and Ho-Wen Hsu
10. Infections in neonates and infants Jacques Couvreur
11. Ocular infection Gordon N. Dutton
12. Laboratory diagnosis of infection David H. M. Joynson and Edward C. Guy
13. Antitoxoplasma chemotherapy Robert E. McCabe
14. Vaccines James L. Fishback and Jack Frenkel
Appendices: Appendix 1. Suggested treatment protocols
Appendix 2. Management of toxoplasma infection in pregnancy
Appendix 3. Hygiene measures to prevent infection
Appendix 4. Classification system and case definitions
Index.

Subject Areas: Parasitology [non-medical PSGH], Paediatric medicine [MJW], Ophthalmology [MJQ], Infectious & contagious diseases [MJCJ], Epidemiology & medical statistics [MBNS]