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TNM Classification of Malignant Tumours

James D. Brierley (Edited by), Brierley (Author), Meredith Giuliani (Edited by), Brian O'Sullivan (Edited by), Brian Rous (Edited by), Elizabeth Van Eycken (Edited by)

9781394216857, Wiley

Paperback / softback, published 10 July 2025

272 pages
21.3 x 14 x 1.8 cm, 0.363 kg

The essential reference on cancer stage returns as a fully revised edition

Describing cancer stage is one of the most important elements of oncological practice. Clinical research and clinical care depend on an accurate assessment of cancer stage and prognostic factors. The TNM Classification of Malignant Tumours serves as the globally recognised standard reference for describing cancer stage and assessing treatment results. Now fully updated to reflect the results of the latest clinical research, it is indispensable for all clinicians, cancer registrars and researchers who work with malignant tumours.

Readers of the ninth edition of TNM Classification of Malignant Tumours will find:

  • Updates in many tumour sites including, nasopharynx, HPV associated oropharynx, lung, thymus, mesothelioma, appendix, anal canal, cervix, vulva and prostate carcinoma;
  • Revised and updated sections on Essential TNM and paediatric cancer staging;
  • New classifications for medulloblastoma, cutaneous lymphoma, parathyroid carcinoma, adrenal medulla and extra-adrenal paraganglia tumours;
  • Revised classification of prognostic factors for many malignancies.

TNM Classification of Malignant Tumours is an essential resource for anyone involved in cancer care, research or cancer control.

Editors-in-chief xi
Editors xiii
Preface xv
Acknowledgements xvi
Organisations Associated with the TNM System xvii
Members of UICC Committees Associated with the TNM System xxviii

Introduction 1

Head and Neck Tumours 17
Oral Cavity and Mucosal Lip 18
Pharynx 23
Larynx 34
Nasal Cavity and Paranasal Sinuses 39
Unknown Primary – Cervical Nodes 43
Malignant Melanoma of Upper Aerodigestive Tract 48
Salivary Glands 50
Thyroid Gland 53
Parathyroid Gland 57

Digestive System Tumours 59
Oesophagus 60
Stomach 66
Small Intestine 70
Appendix 72
Colon and Rectum 75
Anal Canal and Perianal Skin 79
Liver 82
Intrahepatic Bile Ducts 85
Gallbladder 87
Perihilar Bile Ducts 89
Distal Extrahepatic Bile Duct 91
Ampulla of Vater 93
Pancreas 95
Well- Differentiated Neuroendocrine Tumours of the Gastrointestinal Tract 98

Lung, Pleural and Thymic Tumours 107
Lung 109
Pleural Mesothelioma 114
Thymus Tumours 118

Tumours of Bone and Soft Tissues 121
Bone 122
Soft Tissues 126
Gastrointestinal Stromal Tumour (GIST) 129

Skin Tumours 133
Carcinoma of Skin (excluding eyelid, head and neck, perianal, vulva and penis) 135
Carcinoma of Skin of the Head and Neck Region 138
Carcinoma of Skin of the Eyelid 141
Melanoma of Skin 144
Merkel Cell Carcinoma of Skin 149

Breast Tumours 151

Gynaecological Tumours 159
Vulva 160
Vagina 163
Cervix Uteri 165
Uterus – Endometrium 169
Uterine Sarcomas 172
Ovarian, Fallopian Tube and Primary Peritoneal Carcinoma 175
Gestational Trophoblastic Neoplasms 180

Urological Tumours 183
Penis 184
Prostate 187
Testis 190
Kidney 194
Renal Pelvis and Ureter 196
Urinary Bladder 198
Urethra 201

Adrenal Cortex 203

Adrenal Medulla and Extra- Adrenal Paraganglia Tumours 205

Ophthalmic Tumours 207
Carcinoma of Conjunctiva 208
Melanoma of Conjunctiva 210
Melanoma of Uvea 213
Retinoblastoma 217
Sarcoma of Orbit 221
Carcinoma of Lacrimal Gland 223

Brain and Spinal Cord 225

Hodgkin Lymphoma 227

Non- Hodgkin Lymphomas 231

Essential TNM 237

Paediatric Tumours 241
Gastrointestinal Tumours 241
Bone and Soft Tissue Tumours 242
Gynaecological Tumours 244
Urological Tumours 245
Ophthalmic Tumours 247
Lymphoma 247
Leukaemia 248
Central Nervous System 249

Subject Areas: Clinical & internal medicine [MJ]
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