The Ruminant Immune System in Health and Disease

This volume reviews the immune system of domestic ruminants, with particular emphasis on mechanisms of immunity and resistance to infectious diseases.

W. Ivan Morrison (Author)

9780521115476, Cambridge University Press

Paperback, published 16 July 2009

600 pages
22.9 x 15.2 x 3.4 cm, 0.87 kg

First published in 1986, this volume reviews the immune system of domestic ruminants, with particular emphasis on mechanisms of immunity and resistance to infectious diseases. Topics of comparative interest in other species are also covered. The cellular components of the immune system are discussed first, including ontogeny, structural organization and how they interact during the generation of immune responses. This is followed by information on specific aspects of humoral and cell-mediated immune responses, and finally a section on the relevance of various types of immune responses in protection against a number of important infectious diseases of ruminants. The papers included were presented originally at an international conference held in Nairobi, Kenya in September 1983. They provide authoritative coverage of a wide range of topics in ruminant immunology. Together, they comprise a valuable reference text for those involved in all aspects of immunological research in ruminants.

List of authors
Preface
1. Evolution and functions of the immune system A. J. S. Davies
Part I. Cellular Components of the Immune System: 2. Lymphocyte subpopulations in the mouse R. Scollay
3. Definition of lymphocyte subpopulations in man P. C. L. Beverley
4. Definition of lymphocyte populations in cattle using lectins C. Fossum
5. Monoclonal antibodies to bovine leucocytes define heterogenicity of target cells for in vitro parasitosis by theileria parva P. A. Lalor, W. I. Morrison and S. J. Black
6. Construction of a library of monoclonal antibodies for the analysis of the major histocompatibility gene complex and the immune system in ruminants W. C. Davis, L. E. Perryman and T. C. McGuire
Part II. The Major Histocompatibility Complex: 7. The human lymphocyte antigen system J. A. Sachs
8. The bovine major histocompatibility complex R. L. Spooner
9.Biochemical analysis of products of the bovine major histocompatibility complex D. Lévy, M. Hoang-Xuan and M. T. Zilber
10. The role of the major histocompatibility complex in immune responses and susceptibility to disease R. V. Blanden
11. The bovine major histocompatibility complex and disease resistance T. E. Adams and M. R. Brandon
Part III. Structural Organization and Ontogeny: 12. The lymphoid apparatus of the sheep and the recirculation of lymphocytes B. Morris N. C. Pedersen and W. Trevella
13. Cellular constituents and structural organization of the bovine thymus and lymph node W. I. Morrison, P. A. Lalor, A. K. Christensen and P. Webster
14. Ontogeny of immune responses in cattle B. I. Osburn
Part IV. Cellular Immune Responses: 15. Regualtory and effector cell interactions in immune responses R. N. Germain
16. The analysis of the effects of lymphokines on cytotoxic T-cell responses M. A. Skinner, N. Christensen and J. Morbrook
17. Bovine mixed leucocyte reactions and generation of cytotoxic cells B. M. Goddeeris, P. A. Lalor and W. I. Morrison
18. Bovine alloreactive cytotoxic T cells A. J. Teale, W. I. Morrison, R. L. Spooner, B. M. Goddeeris, C. M. Groocock and D. A. Stagg
19. Antibody-dependent cellular cytotoxicity and natural killer cell activity in cattle: mechanisms of recovery from infectious diseases M. P. Lawman, D. Gauntlett and F. Gallery
Part V. Humoral Immune Responses: 20. Structure and function of immunoglobulins: the symbiotic interplay between parasites and antibodies R. Hamers, W. van der Loo and P. De Baetselier
21. Biological properties of bovine immunoglobulins and systemic antibody responses A. J. Musoke, F. R. Rurangirwa and V. M. Nantulya
22. The physiology of secretory immunity J. G. Hall
23. The mucosal immune system with particular reference to ruminant animals A. K. Lascelles, K. J. Beh, T. K. Mukkur and D. L. Watson
Part VI. Role of Immune Responses in Protection Against Infectious Diseases: 24. Effector mechanisms against viral infections L. D. Pearson and K. A. Knisley
25. Immunogenicity of different physical forms of viral antigenic subunits B. Morein
26. Mucosal mast cells, basophils, immediate hypersensitivity reactions and protection against gastrointestinal nematodes H. R. P. Miller
27. Host responses which control Trypanosoma brucei parasites S. J. Black
28. Studies on the protection of cattle against Babesia bovis infection D. F. Mahoney
29. Protective immune responses in bovine theileriosis W. I. Morrison, D. L. Emery, A. J. Teale and B. M. Goddeeris.

Subject Areas: Agriculture & farming [TV]