The Paracellular Channel
Biology, Physiology, and Disease

Presents a cohesive view of the fundamental principles and background information on diverse paracellular channels and their roles in human diseases

Jianghui Hou (Author)

9780128146354, Elsevier Science

Paperback, published 9 June 2018

248 pages
22.9 x 15.1 x 1.7 cm, 0.48 kg

The Paracellular Channel: Biology, Physiology and Disease serves as the first volume to offer a cohesive and unifying picture of the critical functions of paracellular channels (tight junctions) in different tissues. This new class of ion channel utilizes a completely different mechanism to create ion passage pathways across the cell junction. This volume outlines common principles that govern the organization and regulation of these diverse cellular structures, describes the methodology of study, and highlights the pathophysiologic consequence of abnormal structure and functions of the paracellular channels in human diseases.

1. Introduction2. Paracellular Channel Formation3. Paracellular Channel Recording4. Paracellular Cation Channel5. Paracellular Anion Channel6. Paracellular Water Channel7. Paracellular Channel in Organ System8. Paracellular Channel in Human Disease9. Paracellular Channel as Drug Target10. Paracellular Channel Evolution11. Perspective

Subject Areas: Cellular biology [cytology PSF]