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The Evidence Base of Clinical Diagnosis
Theory and Methods of Diagnostic Research
J. André Knottnerus (Edited by), Frank Buntinx (Edited by)
9781405157872, Wiley
Paperback / softback, published 10 October 2008
320 pages
23.5 x 15.8 x 1.9 cm, 0.499 kg
"An invaluable reference ophthalmologists involved in conduting or interpreting studies on diagnostic research." (Eye News, 1 October 2010)“ This is a thorough compilation of clinical research methods and practices.” (Doody's Reviews, March 2009)
This unique book presents a framework for the strategy and methodology of diagnostic research, in relation to its relevance for practice. Now in its second edition The Evidence Base of Clinical Diagnosis has been fully revised and extended with new chapters covering the STARD guidelines (STAndards for the Reporting of Diagnostic accuracy studies) and the multivariable analysis of diagnostic data. With contributions from leading international experts in evidence-based medicine, this book is an indispensable guide on how to conduct and interpret studies in clinical diagnosis. It will serve as a valuable resource for all investigators who want to embark on diagnostic research and for clinicians, practitioners and students who want to learn more about its principles and the relevant methodological options available.
List of Contributors, vii Preface, xi 1 General introduction: evaluation of diagnostic procedures, 1 2 The architecture of diagnostic research, 20 3 Assessment of the accuracy of diagnostic tests: the cross-sectional study, 42 4 Diagnostic testing and prognosis: the randomized controlled trial in test evaluation research, 63 5 The diagnostic before–after study to assess clinical impact, 83 6 Designing studies to ensure that estimates of test accuracy will travel, 96 7 Analysis of data on the accuracy of diagnostic tests, 118 8 Multivariable analysis in diagnostic accuracy studies: what are the possibilities?, 146 9 Standards for reporting on diagnostic accuracy studies, 167 10 Guidelines for conducting systematic reviews of studies evaluating the accuracy of diagnostic tests, 180 11 Producing and using clinical prediction rules, 213 12 Clinical problem solving and diagnostic decision making: a selective review of the cognitive research literature, 237 13 Improving test ordering and its diagnostic cost-effectiveness in clinical practice—bridging the gap between clinical research and routine health care, 256 14 Epilogue: overview of evaluation strategy and challenges, 273 Index, 285
J. Andre Knottnerus, Frank Buntinx, and Chris van Weel
R. Brian Haynes and John J. You
J. Andre Knottnerus and Jean W. Muris
Jeroen G. Lijmer and Patrick M. M. Bossuyt
J. Andre Knottnerus, Geert-Jan Dinant, and Onno P. Van Schayck
Les M. Irwig, Patrick M. M. Bossuyt, Paul P. Glasziou, Constantine Gatsonis, and Jeroen G. Lijmer
J. Dik F. Habbema, Rene Eijkemans, Pieta Krijnen, and J. Andre Knottnerus
Frank Buntinx, Bert Aertgeerts, Marc Aerts, Rudi Bruyninckx, J. Andre Knottnerus, Ann van den Bruel, and Jef van den Ende
Patrick M. M. Bossuyt and Nynke Smidt
Frank Buntinx, Bert Aertgeerts, and Petra Macaskill
Tom Fahey and Johan van der Lei
Alan Schwartz and Arthur S. Elstein
Ron Winkens, Trudy van der Weijden, Hans Severens, and Geert-Jan Dinant
J. Andre Knottnerus, Ann van den Bruel, and Frank Buntinx
Subject Areas: Medicine: general issues [MB]
