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Textbook of Influenza
Robert G. Webster (Author), Arnold S. Monto (Author), Thomas J. Braciale (Author), Robert A. Lamb (Author)
9780470670484, Wiley
Hardback, published 13 September 2013
520 pages
25.4 x 19.6 x 2.8 cm, 1.284 kg
The Textbook of Influenza is a comprehensive resource covering all aspects of influenza, from the genetic and molecular biology of the virus through to clinical aspects of the disease and the latest drug developments and treatments. This new edition has been completely revised and reflects the integration of disciplines concerning the emergence, evolution, pathogenesis and control of influenza viruses in the field of human and veterinary public health. Textbook of Influenza examines the lessons learnt from the latest pandemic and provides the current state of knowledge for many yet unresolved issues related to virus origin, spread, pathogenesis and disease severity to better prepare for future pandemics. It covers the background to recent advances in influenza genomics and reverse genetics which have allowed the identification of virus virulence factors and the analysis and reconstruction of influenza viruses such as the 1918 Spanish flu strain. This new edition is divided into eight key sections, containing chapters co-written by international experts from both the clinical and scientific communities, covering: Textbook of Influenza is for all those working in the area of influenza including clinical and basic scientists, immunologists, molecular and structural virologists, public health officials and global pandemic control planners.
• Influenza Perspectives
• Structure and Replication
• Evolution and Ecology
• Epidemiology and Surveillance
• Immunology
• Vaccines and Vaccine Development
• Clinical Aspects and Antivirals
• Public Health
List of contributors, ix Foreword to the second edition, xiv Preface to the second edition, xvi Acknowledgments, xvii PART 1 Influenza: Perspective 1 Human influenza: One health, one world, 3 2 Influenza pandemics: History and lessons learned, 20 PART 2 Structure and replication 3 Structure, disassembly, assembly, and budding of influenza viruses, 37 4 The virus genome and its replication, 57 5 Influenza glycoproteins: Hemagglutinin and neuraminidase, 67 6 Proton channels of influenza A and B viruses, 101 7 The NS1 protein: A master regulator of host and viral functions, 114 8 Structure and function of the influenza virus replication machinery and PB1-F2, 133 9 The genome and its manipulation: Recovery of the 1918 virus and vaccine virus generation, 146 10 Pathogenesis, 157 PART 3 Evolution and ecology of influenza viruses 11 Ecology and evolution of influenza viruses in wild and domestic birds, 175 12 Influenza in swine, 190 13 Equine/Canine/Feline/Seal influenza, 203 14 Emergence and Evolution of the 1918, 1957, 1968, and 2009 pandemic virus strains, 218 PART 4 Epidemiology and surveillance 15 Influenza surveillance and laboratory diagnosis, 231 16 Epidemiology of influenza, 250 PART 5 Immunology of influenza 17 Innate immunity, 269 18 Antibody-mediated immunity, 283 19 Cell-mediated immunity, 298 PART 6 Vaccines and vaccine development 20 Immunogenicity, efficacy of inactivated/live virus seasonal and pandemic vaccines, 313 21 New approaches to vaccination, 327 22 Control of influenza in animals, 337 23 Influenza vaccine production, 352 PART 7 Clinical aspects and antivirals 24 Human influenza: Pathogenesis, clinical features, and management, 373 25 Antivirals: Targets and use, 392 26 The control of influenza and cost-effectiveness of interventions, 419 27 Applications of quantitative modeling to influenza virus transmission dynamics, antigenic and genetic evolution, and molecular structure, 434 28 Pandemic preparedness and response, 453 29 Influenza: The future, 470 PART 8 The outbreak of H7N9 30 Appendix, 479
Daniel B. Jernigan and Nancy J. Cox
Arnold S. Monto and Robert G. Webster
Debiprosad Nayak, Sakar Shivakoti, Rilwan A. Balogun, Gwendolyn Lee, and Z. Hong Zhou
Robert M. Krug and Ervin Fodor
Rupert J. Russell, Steven J. Gamblin, and John J. Skehel
Chunlong Ma, Lawrence H. Pinto, and Robert A. Lamb
Robert M. Krug and Adolfo García-Sastre
Andrew Mehle and Jonathan A McCullers
Gabriele Neumann and Yoshihiro Kawaoka
Hans Dieter Klenk, Wolfgang Garten, and Mikhail Matrosovich
Ron A.M. Fouchier and Yi Guan
Richard Webby and Juergen Richt
Thomas M. Chambers, Edward J. Dubovi, and Ruben O. Donis
Taia T. Wang and Peter Palese
Maria Zambon
Marc-Alain Widdowson and Arnold S. Monto
Akiko Iwasaki and Malik Peiris
Nicole Baumgarth,Michael C. Carroll, and Santiago Gonzalez
Stephen J. Turner, Peter C. Doherty, and Anne Kelso
Wendy A. Keitel, Kathleen M. Neuzil, and John Treanor
Chih-Jen Wei, Damian C. Ekiert, Gary J. Nabel, and Ian A. Wilson
Ilaria Capua and Dennis J. Alexander
Klaus Stöhr
Frederick G. Hayden and Menno D. de Jong
Michael G. Ison and Alan Hay
Carolyn B. Bridges, Samuel K. Peasah, and Martin I. Meltzer
Marc Lipsitch and Derek Smith
Jonathan S. Nguyen-Van-Tam and Joseph Bresee
Thomas J. Braciale
Thomas J. Bracial
Subject Areas: Other branches of medicine [MM]
