TDP-43 and Neurodegeneration
From Bench to Bedside

Comprehensive reference covering the fundamentals of TDP-43 structure, folding, function, pathology, pathomechanisms, and current and future therapeutics

Vijay Kumar (Edited by), Manoj Kumar Jaiswal (Edited by)

9780128200667

Paperback, published 27 October 2021

270 pages
22.9 x 15.2 x 1.8 cm, 0.41 kg

Approx.256 pages

1. TDP-43: Past, Present and Future
2. Structural studies of TDP-43
3. TDP-43 mutations and Amyotrophic Lateral Sclerosis
4. Post translational modifications of TDP-43
5. TDP-43 and Autophagy
6. TDP-43 and Alzheimer Disease
7. TDP-43 and Stress granules
8. Repeat domains in TDP-43
8. Systems Biology of TDP-43
9. Animal models of TDP-43 in ALS
10. Therapeutic modulations of TDP-43

Subject Areas: Neurosciences [PSAN], Neurology & clinical neurophysiology [MJN], Medical research [MBGR]