Targeting Cell Survival Pathways to Enhance Response to Chemotherapy

Successful methodologies for suppressing the cell survival pathways that contribute to chemotherapy resistance

Benjamin Bonavida (Series edited by), Daniel E. Johnson (Volume editor)

9780128164327

Hardback, published 28 March 2018

308 pages
23.4 x 19 x 2.3 cm, 0.77 kg

Approx.292 pages

1. Targeting Members of the Epidermal Growth Factor Receptor Family to Improve Response to Chemotherapy2. Targeting the Hepatocyte Growth Factor Receptor to Overcome Resistance to Targeted Therapies3. Roles for AXL and MERTK in Resistance to Cytotoxic and Targeted Therapies4. The JNK Pathway in Drug Resistance5. Fibroblast Growth Factor Receptor (FGFR) Inhibitors: Enhancing Therapeutic Strategies for Solid Tumors6. PIK3CA Mutations in Colorectal and Breast Cancer: Impact on Oncogenesis and Response to Nonsteroidal Anti-inflammatory Drugs7. STAT3 as a Major Contributor to Chemoresistance8. Targeting the Hippo Pathway to Improve Response to Chemotherapy9. Modulation of the Epigenome (Methylome) to Improve Chemotherapeutic Efficacy10. Targeting the ATR Signaling Pathway to Overcome Chemoresistance in Cancer11. PARP Inhibition to Enhance Response to Chemotherapy12. Autophagy Inhibition and Chemosensitization in Cancer Therapy13. Targeting Necroptosis in Anti-Tumor Therapy

Subject Areas: Oncology [MJCL], Personal & public health [MBNH]