• Systematic Reviews in Health Research: Meta–Analysis in Context, 3rd Edition (Hardback) 9781405160506
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Systematic Reviews in Health Research
Meta-Analysis in Context

Matthias Egger (Edited by), Julian P. T. Higgins (Edited by), George Davey Smith (Edited by)

9781405160506, Wiley

Hardback, published 26 May 2022

608 pages
25.7 x 17.8 x 3.6 cm, 1.406 kg

Systematic Reviews in Health Research

Explore the cutting-edge of systematic reviews in healthcare

In this Third Edition of the classic Systematic Reviews textbook, now titled Systematic Reviews in Health Research, a team of distinguished researchers deliver a comprehensive and authoritative guide to the rapidly evolving area of systematic reviews and meta-analysis. The book demonstrates why systematic reviews—when conducted properly—provide the highest quality evidence on clinical and public health interventions and shows how they contribute to inference in many other contexts. The new edition reflects the broad role of systematic reviews, including:

  • Twelve new chapters, covering additional study designs, methods and software, for example, on genetic association studies, prediction models, prevalence studies, network and dose-response meta-analysis
  • Thorough update of 15 chapters focusing on systematic reviews of interventions
  • Access to a companion website offering supplementary materials and practical exercises (www.systematic-reviews3.org)

A key text for health researchers, Systematic Reviews in Health Research is also an indispensable resource for practitioners, students, and instructors in the health sciences needing to understand research synthesis.

Preface xix

Tribute xxi

List of Contributors xxviii

About the Companion Website xxxiii

CHAPTER 1 Systematic Reviews in Health Research: An Introduction 1
Matthias Egger, Julian P.T. Higgins, and George Davey Smith

PART I Principles and Procedures 17

CHAPTER 2 Principles of Systematic Reviewing 19
Julian P.T. Higgins, George Davey Smith, Douglas G. Altman, and Matthias Egger

CHAPTER 3 Identifying Randomized Controlled Trials 36
Julie Glanville and Carol Lefebvre

CHAPTER 4 Assessing the Risk of Bias in Randomized Trials 55
Matthew J. Page, Douglas G. Altman, and Matthias Egger

CHAPTER 5 Investigating and Dealing with Publication Bias and Other Reporting Biases 74
Matthew J. Page, Jonathan A.C. Sterne, Julian P.T. Higgins, and Matthias Egger

CHAPTER 6 Managing People and Data 91
Eliane Rohner, Julia Bohlius, Bruno R. da Costa, and Sven Trelle

CHAPTER 7 Reporting and Appraisal of Systematic Reviews 109
Larissa Shamseer, Beverley Shea, Brian Hutton, and David Moher

PART II Meta-Analysis 129

CHAPTER 8 Effect Measures 131
Julian P.T. Higgins, Jonathan J. Deeks, and Douglas G. Altman

CHAPTER 9 Combining Results Using Meta-Analysis 159
Jonathan J. Deeks, Richard D. Riley, and Julian P.T. Higgins

CHAPTER 10 Exploring Heterogeneity 185
Julian P.T. Higgins and Tianjing Li

CHAPTER 11 Dealing with Missing Outcome Data in Meta-Analysis 204
Ian R. White and Dimitris Mavridis

CHAPTER 12 Individual Participant Data Meta-Analysis 220
Mark C. Simmonds and Lesley A. Stewart

CHAPTER 13 Network Meta-Analysis 238
Georgia Salanti and Julian P.T. Higgins

CHAPTER 14 Dose-Response Meta-Analysis 258
Nicola Orsini, Susanna C. Larsson, and Georgia Salanti

PART III Specific Study Designs 271

CHAPTER 15 Systematic Reviews of Nonrandomized Studies of Interventions 273
Jelena Savovic, Penny F. Whiting, and Olaf M. Dekkers

CHAPTER 16 Systematic Reviews of Diagnostic Accuracy 296
Yemisi Takwoingi and Jonathan J. Deeks

CHAPTER 17 Systematic Reviews of Prognostic Factor Studies 324
Richard D. Riley, Karel G.M. Moons, Douglas G. Altman, Gary S. Collins, and Thomas P.A. Debray

CHAPTER 18 Systematic Reviews of Prediction Models 347
Gary S. Collins, Karel G.M. Moons, Thomas P.A. Debray, Douglas G. Altman, and Richard D. Riley

CHAPTER 19 Systematic Reviews of Epidemiological Studies of Etiology and Prevalence 377
Matthias Egger, Diana Buitrago-Garcia, and George Davey Smith

CHAPTER 20 Meta-Analysis in Genetic Association Studies 396
Gibran Hemani

PART IV Cochrane and Guideline Development 413

CHAPTER 21 Cochrane: Trusted Evidence. Informed Decisions. Better Health 415
Gerd Antes, David Tovey, and Nancy Owens

CHAPTER 22 Using Systematic Reviews in Guideline Development: The GRADE Approach 424
Holger J. Schünemann

PART V Outlook 449

CHAPTER 23 Innovations in Systematic Review Production 451
Julian Elliott and Tari Turner

CHAPTER 24 Future for Systematic Reviews and Meta-Analysis 463
Shah Ebrahim and Mark D. Huffman

PART VI Software 481

CHAPTER 25 Meta-Analysis in Stata 483
David J. Fisher, Marcel Zwahlen, Matthias Egger, and Julian P.T. Higgins

CHAPTER 26 Meta-Analysis in R 510
Guido Schwarzer

CHAPTER 27 Comprehensive Meta-Analysis Software 535
Michael Borenstein

Index 549

Subject Areas: Medicine: general issues [MB]
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