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Stress Resilience
Molecular and Behavioral Aspects

Examines the molecular and cellular mechanisms, environmental factors and life experiences that contribute to stress resilience

Alon Chen (Edited by)

9780128139837

Paperback / softback, published 1 November 2019

390 pages
23.4 x 19 x 2.5 cm, 0.81 kg

"Hans Selye, in his seminal 1936 note to Nature, introduced the “general adaptation syndrome?. That is, the ability of the organism to adapt itself to new conditions: the basis for our understanding of stress resilience. Alon Chen (Editor), a brilliant stress neuroscientist, has recruited top experts to submit 22 chapters that make this book a valuable, cutting edge contribution to stress resilience. I strongly commend “Stress Resilience? for fundamental and clinical research scientists as well as students and clinicians, especially in the fields of Neuroscience and molecular neurobiology and genetics, Neurology, Medicine, Endocrinology, Psychiatry, Psychology and related disciplines." -- George Fink (MD, DPhil, FRCPE, FRSB, FRSE) Professorial Research Fellow, the Florey Institute of Neuroscience and Mental Health, University of Melbourne, Victoria, Australia

Stress Resilience: Molecular and Behavioral Aspects presents the first reference available on the full-breadth of cutting-edge research being carried out in this field. It includes a wide range of basic molecular knowledge on the potential associations between resilience phenomenon and biochemical balance, but also focuses on the molecular and cellular mechanisms underlying stress resilience. World-renowned experts provide chapters that cover everything from the neural circuits of resilience, the effects of early-life adversity, and the transgenerational inheritance of resilience.

This unique and timely book will be a go-to resource for neuroscientists and biological psychiatrists who want to improve their understanding of the consequences of stress and on how some people are able to avoid it.

1. A life-course, epigenetic perspective on resilience in brain and body
2. Cognitive and behavioral components of resilience to stress
3. Resilience as a process instead of a trait
4. The brain mineralocorticoid receptor: A resilience factor for psychopathology?
5. GABAB receptors and stress resilience: A tale of two isoforms
6. Sex differences in the programming of stress resilience
7. Active resilience in response to traumatic stress
8. Rhythms of stress resilience
9. Mitochondrial function and stress resilience
10. Understanding resilience: Biological approaches in at-risk populations
11. Stress resilience as a consequence of early-life adversity
12. Mechanisms by which early-life experiences promote enduring stress resilience or vulnerability
13. Child abuse and neglect: Stress responsivity and resilience
14. How genes and environment interact to shape risk and resilience to stress-related psychiatric disorders
15. Molecular characterization of the resilient brain: Transcriptional and epigenetic mechanisms
16. The role of the CRF-Urocortin system in stress resilience
17. Intergenerational transmission of stress vulnerability and resilience
18. stress and its effects across generations
19. Corticolimbic stress-regulatory circuits, hypothalamo-pituitary-adrenocortical adaptation and resilience
20. Biomarkers of resilience and susceptibility in rodent models of stress
21. Maladaptive learning and the amygdala - prefrontal circuit
22. Endocannabinoid signaling and stress resilience

Subject Areas: Neurosciences [PSAN]

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