Stem Cells in Development and Disease

This new volume in Current Topics in Developmental Biology concentrates on Stem Cells in Development and Disease and with an international team of authors, this is a must-have addition for researchers and students alike

Michael Rendl (Volume editor)

9780124160224, Elsevier Science

Hardback, published 26 March 2014

472 pages
22.9 x 15.1 x 2.9 cm, 0.86 kg

"...contains especially strong content on adult stem cells, as well as additional chapters that focus on the more universal themes of pluripotency itself, cancer stem cells, and aging of resident adult stem cell populations." --The Quarterly Review of Biology

This new volume of Current Topics in Developmental Biology covers Stem Cells in Development and Disease. The chapters provide a comprehensive set of reviews covering such topics as the mechanisms of pluripotency in vivo and in vitro, hematopoietic stem cell development, intestinal stem cells and their defining niche, epithelial stem cells in adult skin, the mammary stem cell hierarchy, satellite cells, neural stem cells of the hippocampus, lung stem and progenitor cells in tissue homeostasis and disease, spermatogonial stem cell functions in physiological and pathological conditions, the origin, biology, and therapeutic potential of facultative adult hepatic progenitor cells, nephron progenitor cells, adult stem cell niches, cancer stem cells, pluripotency and cellular heterogeneity, and cellular mechanisms of somatic stem cell aging

1. Mechanisms of Pluripotency In Vivo and In Vitro
2. Hematopoietic Stem Cell Development: An Epigenetic Journey
3. Intestinal Stem Cells and their Defining Niche
4. Epithelial Stem Cells in Adult Skin
5. The Mammary Stem Cell Hierarchy
6. Satellite Cells: The Architects of Skeletal Muscle
7. Neural Stem Cells of the Hippocampus: Development, Physiology Regulation and Dysfunction in Disease
8. Lung Stem and Progenitor Cells in Tissue Homeostasis and Disease
9. Spermatogonial Stem Cell Functions in Physiological and Pathological Conditions
10. The Origin, Biology, and Therapeutic Potential of Facultative Adult Hepatic Progenitor Cells
11. Nephron Progenitor Cells: Shifting the Balance of Self-Renewal and Differentiation
12. Adult Stem Cell Niches: Cellular and Molecular Components
13. Cancer Stem Cells, Pluripotency, and Cellular Heterogeneity: A WNTer Perspective
14. Cellular Mechanisms of Somatic Stem Cell Aging

Subject Areas: Cellular biology [cytology PSF], Developmental biology [PSC], Cytology [MFCC], Medical research [MBGR]