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    Stem Cell in Medicine

    Includes fundamental and topical subjects on stem cells used in Medicine, such as in drug screening and disease treatment

    Akon Higuchi (Volume editor), Yinghong Zhou (Volume editor), Shih-Hwa Chiou (Volume editor)

    9780443134111, Elsevier Science

    Hardback, published 31 August 2023

    300 pages
    22.9 x 15.1 x 2.3 cm, 0.45 kg

    Stem Cells in Medicine, Volume 199 in the Progress in Molecular Biology and Translational Science series, provides the most topical and informative research in the field of stem cells. Sections in this new release update on an Introduction to stem cells, Stem cell engineering, Xeno-free culture and proliferation of hPSCs on 2D biomaterials, 3D scaffold preparation for stem cell culture and differentiation, GMP grade production of hPSCs, Human hepatic stem cell assay, Cardiomyocyte cell sheets derived from hPSCs and muscle cells for myocardial infarction treatment, Stem cell therapy for osteoarthritis, hPSC-derived RPE transplantation for the treatment of macular degeneration, and much more.

    The book provides not only fundamental aspects and cultural and production methods of stem cells, but also the critical engineering aspects of stem cells such as drug screening using hepatocytes and disease treatment by transplantation of retinal pigment epithelium and cardiomyocytes which are derived from human pluripotent stem cells.

    Preface

    Akon Higuchi, Yinghong Zhou and Shih-Hwa Chiou

    1. Introduction to stem cells

      2. Zeyu Tian, Tao Yu, Jun Liu, Ting Wang, and Akon Higuchi

    2. Engineered adult stem cells: current clinical trials status of disease treatment

      3. Pingping Han, Corey Stephan Moran, Chun Liu, Rebecca Griffiths, Yinghong Zhou, and

      Sašo Ivanovski

    3. Xeno-free culture and proliferation of hPSCs on 2D biomaterials

      4. Ting Wang, Tao Yu, Chang-Yen Tsai, Zhao-Yu Hong, Wen-Hui Chao, Yi-Shuo Su, Suresh Kumar Subbiah, Remya Rajan Renuka, Shih-Tien Hsu, Gwo-Jang Wu, and Akon Higuchi

    4. Stem cell culture and differentiation in 3-D scaffolds

      5. Yasuhiko Tabata, Idaszek Joanna, and Akon Higuchi

    5. Current trends and promising clinical utility of IPSC-derived MSC (iMSC)

      6. Shih-Hwa Chiou, Alan Han Kiat Ong , Shih-Jie Chou, Ahmed Faris Aldoghachi, Jit Kai Loh, Nalini Devi Verusingam,

      Yi-Ping Yang, and Yueh Chien

    6. Drug metabolic activity as a selection factor for pluripotent stem cell-derived hepatic progenitor cells

      7. Saeko Akiyama, Noriaki Saku, Shoko Miyata, Kenta Ite, Hidenori Nonaka, Masashi Toyoda, Akihide Kamiya, Tohru Kiyono, Tohru Kimura, Mureo Kasahara, and Akihiro Umezawa

    7. Cardiac cell sheet engineering for regenerative medicine and tissue modeling

      8. Katsuhisa Matsuura and Tatsuya Shimizu

    8. Mesenchymal stem cells in osteoarthritis: The need for translation into clinical therapy

      9. Feng Gao, Xinzhan Mao, and Xiaoxin Wu

    9. hPSC-derived RPE transplantation for the treatment of macular degeneration

      10. Qian Liu, Jun Liu, and Akon Higuchi

    10. Universal and hypoimmunogenic pluripotent stem cells for clinical usage

      11. Tzu-Cheng Sung, Kailibinuer Maitiruze, Jiandong Pan,

      Jian Gong, Yongheng Bai, Xiaodong Pan, and Akon Higuchi

    11. Clinical Usage of Dental Stem Cells and Their Derived Extracellular Vesicles

      12. Yinghong Zhou, Tian Xu, Cong Wang, Pingping Han, and Sašo Ivanovski

    12. Vascularization of cutaneous wounds by stem cells

      13. Motaharesadat Hosseini and Abbas Shafiee

    13. Application of IPSC and Müller glia derivatives in retinal degenerative diseases

      14. Guoge Han, Pinghui Wei, and Quanhong Han

    14. Pluripotent Stem Cells as a Therapy for Type 1 Diabetes

      15. Bernard E. Tuch, Iris S. Cheng, Hoang Phuc Dang, Hui Chen, and Tim R. Dargaville

    15. Stem cell challenges and opportunities

    Kenta Ite, Masashi Toyoda, Saeko Akiyama, Shin Enosawa, Saeko Yoshioka,

    Takaaki Yukitake, Mayu Yamazaki-Inoue, Kuniko Tatsumi, Hidenori Akutsu, Hiroshi Nishina, Toru Kimura, Naoko Otani, Atsuko Nakazawa, Akinari Fukuda, Mureo Kasahara, and Akihiro Umezawa

    Subject Areas: Molecular biology [PSD], Biochemistry [PSB]
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