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Stellate Cells in Health and Disease
Up-to-date knowledge and perspectives of the established and putative functions of stellate cells in various pathophysiological conditions that affect the structure and functions of the liver
Chandrashekhar Gandhi (Edited by), Massimo Pinzani (Edited by)
9780128001349
Hardback, published 14 April 2015
336 pages, 25 illustrations (25 in full color)
23.4 x 19 x 2.4 cm, 0.79 kg
Stellate Cells in Health and Disease is a comprehensive reference providing the most up-to-date knowledge and perspectives on the function of stellate cells affecting the liver and other organs. The text presents comprehensive coverage of their already established role in hepatic fibrosis along with the newer emerging evidence for stellate cell participation in the liver cell (hepatocyte) survival and regeneration, hepatic immunobiology, transplant tolerance, and liver cancer. Chapters describe both animal and human research and the relevance of findings from animal research to human pathophysiology, and also contain sections on future directions which will be of special interest to basic and clinical researchers working on liver fibrosis, hepatic biology, and pathobiology.
Chapter 1. History and Early Work
Chapter 2. Stellate Cell Culture Models
Chapter 3. Hepatic Fibrosis: A Global Clinical Problem
Chapter 4. Stellate Cells and Hepatic Fibrosis
Chapter 5. Cytokin Production and Signaling in Stellate Cells
Chapter 6. Stellate Cells, Portal Myofibroblasts and Epithelial-Mesenchymal Transition
Chapter 7. Matrix Melalloproteinases and their Inhibitors
Chapter 8. Matrix Melalloproteinases and their Inhibitors
Chapter 9. Stellate Cells and Liver Cancer
Chapter 10. Morphogens and hepatic stellate cell fate regulation
Chapter 11. Stellate Cells in alcoholic Steatohepatitis
Chapter 12. Stellate Cells as target for Reversal of Fibrosis/Cirrhosis
Chapter 13. Interactions of Stellate Cells with other Nonparenchymal Cells
Chapter 14. Stellate Cells in Regulation of Hepatocyte Survival and Functions
Chapter 15. Stellate Cells in hepatic Immunobiology
Chapter 16. Stellate Cell Depletion Models
Chapter 17. Stellate Cells in Nonhepatic Organs
Subject Areas: Cellular biology [cytology PSF], Neurosciences [PSAN], Neurology & clinical neurophysiology [MJN], Cellular physiology [MFGC]
