Solid-Phase Organic Synthesis

Kevin Burgess (Author)

9780471318255, Wiley

Hardback, published 16 December 1999

294 pages
24 x 16 x 2.7 cm, 0.608 kg

"Collects and critiques key developments in the field...explains different perspectives on various aspects." (SciTech Book News, March 2001)
"This book seeks to highlight and critique key developments in solid-phase organic synthesis...Overall, the book effectively realizes its goal..." (Journal of the American Chemical Society, Vol. 123, No. 7)
"...an excellent starting point for chemists interested in solid-phase organic synthesis. Certainly, this book should be considered as an addition to any medicinal chemists library." (Journal of Medicinal Chemistry Vol. 44, No. 24, 2001)
"...brings together...the latest research in the field, highlighting and reviewing some of the major developments." (Chimie Nouvelle)

Die Festphasensynthese spielt eine Schlüsselrolle in der kombinatorischen Chemie, einer neuen Methode der Wirkstofforschung zur raschen, weitgehend automatisierten Synthese, Testung und Archivierung chemischer Verbindungen. Dieses in sich geschlossene Werk beschreibt die wichtigsten Entwicklungen auf diesem Gebiet innerhalb der vergangenen drei Jahre, unter anderem die Festphasensynthese von Naturstoffderivaten und die Palladium-katalysierte C-C-Bindungsknüpfung. (01/00)

Solid Phase Syntheses of Guanidines (K. Burgess & J. Chen).

Palladium-catalyzed Carbon-carbon Bond Formation on Solid Supports (M. Todd & C. Abell).

Benzofused Heterocycles via Solid-phase S_NAr Reactions (M. Schwarz & M. Gallop).

Solid-phase Synthesis of Sequence-specific Phenylacetylene Oligomers (J. Moore, et al.).

Polymer-assisted Solution Phase Methods for Chemical Library Synthesis (D. Flynn, et al.).

Solid-phase Organic Synthesis on Radiation-grafted Polymer Surfaces: Application of SynPhase(TM) Crowns to Multiple Parallel Syntheses (I. James, et al.).

Vibrational Spectroscopy for Optimization of Solid-phase Organic Syntheses (B. Yan).

Recent Advances in Solid-phase Synthesis of Natural Products (L. Wilson).

Subject Areas: Chemistry [PN]