Smart Polymeric Nano-Constructs in Drug Delivery
Concept, Design and Therapeutic Applications

Provides a comprehensive overview of the potential role of polymeric system in targeted drug delivery

Suresh P Vyas (Edited by), Udita Agrawal (Edited by), Rajeev Sharma (Edited by)

9780323912488, Elsevier Science

Paperback / softback, published 17 November 2022

624 pages
23.5 x 19 x 3.8 cm, 0.45 kg

Smart Polymeric Nano-Constructs in Drug Delivery: Concept, Design and Therapeutic Applications provides a thorough discussion of the most state of the art material and polymer exploitations for the delivery of bioactive(s) as well as their current and clinical status. The book enables researchers to prepare a variety of smart drug delivery systems to investigate their properties as well as to discover their uses and applications. The novelty of this approach addresses an existing need of exhaustively understanding the potential of the materials including polymeric drug delivery systems that are smartly designed to deliver bioactive(s) into the body at targeted sites without showing side effects. The book is helpful for those in the health sector, specifically those developing nanomedicine using smart material-based nano-delivery systems. Polymers have unique co-operative properties that are not found with low-molecular-weight compounds along with their appealing physical and chemical properties, constituting the root of their success in drug delivery. Smart Polymeric Nano-Constructs in Drug Delivery: Concept, Design and Therapeutic Applications discusses smart and stimuli responsive polymers applicable in drug delivery, followed detailed information about various concepts and designing of polymeric novel drug delivery systems for treatment of various type of diseases, also discussing patents related to the field. The book helps readers to design and develop novel drug delivery systems based on smart materials for the effective delivery of bioactive that take advantage of recent advances in smart polymer-based strategies. It is useful to those in pharmaceutical sciences and related fields in developing new drug delivery systems.

1. Introduction to smart polymers and their applications
2. Thermoresponsive polymers: Phase behaviour, drug delivery and biomedical applications
3. pH-sensitive polymeric nanocarriers for enhanced intracellular drug delivery
4. Photo-responsive nanocarriers for delivery of bioactives
5. Magnetically responsive polymer gels and elastomers for drug delivery
6. Bioadhesive and phase-change polymers for drug delivery
7. Block copolymer micelles as long-circulating drug vehicles
8. Polymer–drug conjugates: origins, progress to date and future directions
9. Molecularly imprinted polymers for drug delivery
10. Dendritic polymer macromolecular carriers for drug delivery
11. Hydrogels: from controlled release to pH-responsive drug delivery
12. Stimuli-responsive protein fibres for advanced applications
13. Smart drug delivery systems and its clinical potential
14. Novel biomimetic polymersomes as polymer therapeutics for drug delivery
15. Bioinspired Platform Conjugated systems for Active Drug Delivery
16. Electrically conductive polymers for drug delivery
17. Polymeric nanomedicine: Principles, Properties, and Regulatory Issues
18. Smart drug delivery systems and their clinical potential
19. Polymer-matrix nanocomposites and its potential applications

Subject Areas: Biotechnology [TCB], Pharmacology [MMG], Pharmaceutical industries [KNDP]