Sertoli Cell Biology

Update on Sertoli/germ cell research over the past 10 years

Michael D. Griswold (Edited by)

9780124170476, Elsevier Science

Hardback, published 2 December 2014

488 pages
22.9 x 15.1 x 2.9 cm, 1.03 kg

"While many articles have appeared in journals on the Sertoli cell, this book provides you a rare treat – an extensive and intensive study on it."
--Biz India

"...a must-have reference for anyone interested in testis development and function. It is one of a kind, offering important and valuable information about the biology of Sertoli cells. Score: 100 - 5 Stars"
--Doody's

Sertoli Cell Biology, Second Edition summarizes the progress since the last edition and emphasizes the new information available on Sertoli/germ cell interactions. This information is especially timely since the progress in the past few years has been exceptional and it relates to control of sperm production in vivo and in vitro.

Preface
1. Sertoli cell anatomy and cytoskeleton
2. Fetal Sertoli cells
3. Early postnatal interactions between Sertoli and germ cells
4. Stem cell Niche
5. Role of DMRT1
6. Hormonal regulation of spermatogenesis through Sertoli cells- Testosterone
7. Activins and inhibins
8. Initiation of spermatogenesis and the cycle of the seminiferous epithelium
9. Retinoic acid metabolism and the cycle of the seminiferous epithelium
10. Sertoli cell specific transcription and the Sertoli cell cycle
11. Micro-RNA and spermatogenesis
12. Large noncoding RNAs (lncRNAs) and lncRNA-mediated epigenetic regulation
13. Biochemistry of Sertoli-Germ cell junctions, spermiation and movement of germ cells across the barrier
14. Immunology of the Testis
15. Diversity and similarities in Sertoli cells from different species
16. Human Sertoli cells and the SCO syndrome
17. Gene Knockouts that affect Sertoli cell function

Subject Areas: Animal physiology [PSVD], Cellular biology [cytology PSF], Developmental biology [PSC]