Freshly Printed - allow 10 days lead
Couldn't load pickup availability
Senescence, Senotherapeutics and Mitochondria
Offers a novel perspective on both basic and clinical sciences for wide group of the well-established academicians, students and researchers
Ufuk Cakatay (Volume editor), Mehmet Can Atayik (Volume editor)
9780443188862, Elsevier Science
Hardback, published 10 July 2023
468 pages
22.9 x 15.1 x 2.2 cm, 0.45 kg
Senescence, Senotherapeutics and Mitochondria, Volume 136 offers updates on this unique topics, with chapters covering Cellular Senescence in Aging: Molecular Basis, Implications and Therapeutic Interventions, Mitochondria-associated Cellular Senescence Mechanisms: Biochemical and Pharmacological Perspectives, Mitochondria in cell senescence: Friend or Foe?, The role of mitochondria and mitophagy in cell senescence, Small molecules targeting mitochondrial dysfunction for potential senotheraputics, Senolytic and senomorphic interventions to defy senescence-associated mitochondrial dysfunction, Mitochondrial targeting peptides and probes, Mitochondria-derived peptides in healthy ageing and therapy of age-related diseases, and much more. Other sections cover Targeting of mitostasis-proteostasis axis by antioxidant polysaccharides in neurodegeneration, Phytotherapeutic targeting of the mitochondria in neurodegenerative disorders, Melatonin as mitochondria-targeted drugs, Coenzyme Q-related compounds to maintain healthy mitochondria during aging, Changing ROS, NAD and AMP: a path to longevity via mitochondrial therapeutics, and more.
1. Cellular Senescence in Aging: Molecular Basis, Implications and Therapeutic Interventions Jemima Princilly, Bhavana Veerabhadrappa, Nagashree N. Rao and Madhu Dyavaiah 2. Mitochondria in cell senescence: A Friend or Foe? Qian Chen, Lindon Young, Robert Barsotti 3. The role of mitochondria and mitophagy in cell senescence Tayyab Ali, Fatma Hussain, Haroon Ur Rashid Kayani, Muhammad Naeem, and Fozia Anjum 4. Mitochondria-associated cellular senescence mechanisms: Biochemical and pharmacological perspectives Mehmet Can Atayik and Ufuk Çakatay 5. Changing ROS, NAD and AMP: A path to longevity via mitochondrial therapeutics Oleh Lushchak, Dmytro Gospodaryov, Olha Strilbytska, and Maria Bayliak 6. Mitochondria-derived peptides in healthy ageing and therapy of age-related diseases Siarhei A. Dabravolski 7. Senolytic and senomorphic interventions to defy senescence-associated mitochondrial dysfunction Jan O. Nehlin 8. Melatonin as mitochondria-targeted drug Sibel Suzen, Luciano Saso 9. Coenzyme Q-related compounds to maintain healthy mitochondria during aging Guillermo López-Lluch 10. Targeting mitochondrial dysfunction to salvage cellular senescence for managing neurodegeneration Komal Sharma, Joyobrata Sarkar, Anchal Trisal, Rishika Ghosh, Anubhuti Dixit, Abhishek Kumar Singh 11. Targeting the microbiota-mitochondria crosstalk in neurodegeneration with senotherapeutics Jan Homolak 12. Therapeutic targeting of mitochondria–proteostasis axis by antioxidant polysaccharides in neurodegeneration Qiangqiang Wang, Muhammad Zeeshan Adil, Xiaoliang Xie, Shihao Zhao, Ju Zhang, and Zebo Huang 13. Phytotherapeutic targeting of the mitochondria in neurodegenerative disorders Priyanka Sarkar, Ashish Kumar, Partha Sarathi Behera, and Kavitha Thirumurugan
Subject Areas: Cellular biology [cytology PSF], Molecular biology [PSD], Biochemistry [PSB]