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Self-Assembled Supramolecular Architectures
Lyotropic Liquid Crystals
Nissim Garti (Edited by), N Garti (Author), Ponisseril Somasundaran (Edited by), Raffaele Mezzenga (Edited by)
9780470281758, Wiley
Hardback, published 6 November 2012
396 pages
24 x 16.5 x 2.5 cm, 0.685 kg
This book will describe fundamentals and recent developments in the area of Self-Assembled Supramolecular Architecture and their relevance to the understanding of the functionality of membranes as delivery systems for active ingredients. As the heirarchial architectures determine their performance capabilities, attention will be paid to theoretical and design aspects related to the construction of lyotropic liquid crystals: mesophases such as lamellar, hexagonal, cubic, sponge phase micellosomes. The book will bring to the reader mechanistic aspects, compositional considerations, transition within phases, solubilization capacities, drug entrapment and release mechanisms and transmembrane, transdermal, and other transport phenomena. It will stress the importance of these mesostructures to crystallization and polymorphism of drugs, fats, and nutraceuticals and will discuss regioselectivity of organic and enzymatic reactions that take place at interfaces and within the channels of the mesophase. The book will bring studies on the use of these mesophase as crystallization or particulation media for the formation of nanoparticles and nanocrystals. Chapters will discuss applications in the areas of pharmaceuticals, food, cosmetics, plastics, paper, agro-chemistry and industrial applications.
Preface vii Contributors xi 1. Physics of Self-Assembly of Lyotropic Liquid Crystals 1 2. Rheological Theory and Simulation of Surfactant Nematic Liquid Crystals 21 3. Dividing Planes of Hexagonal HII Mesophase 79 4. Nanocharacterization of Lyotropic Liquid Crystalline Systems 97 5. Self-Assembly in Lipidic Particles 129 6. Hierarchically Organized Systems Based on Liquid Crystalline Phases 157 7. Synthesis and Alignment of Nanostructured Materials Using Liquid Crystals 193 8. Recent Developments in Lyotropic Liquid Crystals as Drug Delivery Vehicles 219 9. Stimuli-Responsive Lipid-Based Self-Assembled Systems 257 10. Nonlamellar Lipid Liquid Crystalline Structures at Interfaces 289 11. Multicompartment Lipid Nanocarriers for Targeting of Cells Expressing Brain Receptors 319 Index 357
Raffaele Mezzenga
Alejandro D. Rey and E. E. Herrera-Valencia
Vesselin Kolev, Abraham Aserin, and Nissim Garti
Patrick G. Hartley and Hsin-Hui Shen
Anan Yaghmur and Otto Glatter
Chandrashekhar V. Kulkarni and Otto Glatter
Idit Amar-Yuli, Abraham Aserin, and Nissim Garti
Dima Libster, Abraham Aserin, and Nissim Garti
Ben J. Boyd and Wye-Khay Fong
Debby P. Chang and Tommy Nylander
Claire Géral, Angelina Angelova, Borislav Angelov, Valérie Nicolas, and Sylviane Lesieur
Subject Areas: Chemistry [PN]
