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Secretory Proteins

Edited by one of the best scientists in the field, this series presents the latest updates in the field of protein chemistry and structural biology

Rossen Donev (Edited by)

9780443158209, Elsevier Science

Hardback, published 17 January 2023

376 pages
22.9 x 15.1 x 2.6 cm, 0.45 kg

Secretory Proteins, Volume 133 in the Advances in Protein Chemistry and Structural Biology series highlights new advances in the field, including chapters on Proprotein Convertases regulate trafficking and maturation of key proteins within the secretory pathway, Secretory Proteins in Cancer Diagnosis, Senescent Cells and SASP in Cancer Microenvironment: new approaches in cancer therapy, Autophagy for secretory protein: Therapeutic targets in cancer, Secretory proteins and pathways of secretion of osteosarcoma, Monocyte secretory proteins as drug targets for arresting progression of atherosclerosis, The secretory phenotypes of envenomed cells: insights into venom cytotoxicity, Macromolecules for secretory pathway in SARS-CoV-2 infection, and much more.

Other sections cover Exploring the role of secretory proteins in the human infectious diseases diagnosis and therapeutics, Secretory proteins in orchestration of microbial pathogenesis- the curious case of Staphylococcus aureus, Influence of pathological mutations in Aspartylglucosylamine Deaspartylase causing Aspartylglucosaminuria: an in silico approach, and Change in conformational dynamics of Lipase A secretory protein upon mutation causing Wolman disease.

1. Proprotein convertases regulate trafficking and maturation of key proteins within the secretory pathway
Laura Cendron, Sylvia Rothenberger, Leonardo Cassari, Monica Dettin, and Antonella Pasquato
2. Exploring the macromolecules for secretory pathway in cancer disease
Chandrabose Selvaraj, Umesh Panwar, Karthik Raja Ramalingam, Rajendran Vijayakumar, and Sanjeev Kumar Singh
3. Current and emerging biomarkers in ovarian cancer diagnosis: CA125 and beyond
Tarang Sharma, Sabah Nisar, Tariq Masoodi, Muzafar A. Macha, Shahab Uddin, Ammira Al-Shabeeb Akil, Tej K. Pandita, Mayank Singh, and Ajaz A. Bhat
4. Senescent cells and SASP in cancer microenvironment: New approaches in cancer therapy
Aysun Ozdemir, Yaprak Dilber Simay Demir, Zeynep Elif Yesilyurt, and Mustafa Ark
5. Autophagy for secretory protein: Therapeutic targets in cancer
Kewal Kumar Mahapatra, Srimanta Patra, Soumya Ranjan Mishra, Bishnu Prasad Behera, Shankargouda Patil, and Sujit Kumar Bhutia
6. The role of SPARC/ON in human osteosarcoma
Consolato M. Sergi
7. The secretory phenotypes of envenomed cells: Insights into venom cytotoxicity
Y. Yong, J.J. Hiu, and M.K.K. Yap
8. Exploring the role of secretory proteins in the human infectious diseases diagnosis and therapeutics
Elora Kalita, Mamta Panda, Abhishek Rao, and Vijay Kumar Prajapati
9. Secretory proteins in the orchestration of microbial virulence: The curious case of Staphylococcus aureus
Dileep Francis, Anusha Bhairaddy, Atheene Joy, Gopika Veeramanickathadathil Hari, and Ashik Francis
10. Structure-based virtual screening to identify potential lipase inhibitors to reduce lipid storage in Wolman disorder
Karthick Vasudevan, S. Udhaya Kumar, A. Mithun, B. Raghavendra, and C. George Priya Doss

Subject Areas: Cellular biology [cytology PSF], Molecular biology [PSD], Biochemistry [PSB], DNA & Genome [PSAK1]

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