Secondary Schizophrenia

This book is the first major attempt to review the diseases that produce schizophrenia-like syndromes, or psychotic symptoms.

Perminder S. Sachdev (Edited by), Matcheri S. Keshavan (Edited by)

9780521856973, Cambridge University Press

Hardback, published 4 February 2010

450 pages, 23 b/w illus. 2 colour illus. 35 tables
25.2 x 19.3 x 2.5 cm, 1.12 kg

' … this book provides a rich and comprehensive review of the many conditions know n to be associated with psychosis, which could be of great value to students and a resource for senior scientists in the field. it is thought-provoking and its treatments of provocative issues resulting from very recent research are timely and enjoyable. The book is particularly satisfying because it excels on so many levels. This includes the clear list-making organization of basic facts characteristic of the allopathic tradition, and the thoughtful attempt at integration of disparate findings into etiopathogenic explanations of signs and symptoms. Adding to this already very useful review of vast swathes of clinically oriented literature is the valiant and nuanced contextualization of otherwise typical textbook fare into the fundamental conceptual conundrm lurking at the heart of the entire book: what is schizophrenia.' The Journal of Psychological Medicine

Schizophrenia may not be a single disease, but the result of a diverse set of related conditions. Modern neuroscience is beginning to reveal some of the genetic and environmental underpinnings of schizophrenia; however, an approach less well travelled is to examine the medical disorders that produce symptoms resembling schizophrenia. This book is the first major attempt to bring together the diseases that produce what has been termed 'secondary schizophrenia'. International experts from diverse backgrounds ask the questions: does this medical disorder, or drug, or condition cause psychosis? If yes, does it resemble schizophrenia? What mechanisms form the basis of this relationship? What implications does this understanding have for aetiology and treatment? The answers are a feast for clinicians and researchers of psychosis and schizophrenia. They mark the next step in trying to meet the most important challenge to modern neuroscience – understanding and conquering this most mysterious of human diseases.

Part I. Introduction: 1. The neurobiology and aetiology of primary schizophrenia: current status Matcheri S. Keshavan and Ripu D. Jindal
2. The concept of organicity and its application to schizophrenia Perminder S. Sachdev
3. Secondary hallucinations Mark Walterfang, Ramon Mocellin, David Copolov and Dennis Velakoulis
Part II. The Neurology of Schizophrenia: 4. The neurologic examination in schizophrenia Richard D. Sanders and Matcheri S. Keshavan
5. Functional neuroimaging in schizophrenia Serge A. Mitelman, Jane Zhang and Monte S. Buchsbaum
Part III. Organic Syndromes of Schizophrenia
Section 1. Epilepsy and Schizophrenia: 6. Schizophrenia-like psychosis and epilepsy Perminder S. Sachdev
7. Understanding the pathophysiology of schizophrenia through the looking glass of forced normalization Ennapadam S. Krishnamoorthy and Seethalakshmi Ramanathan
Section 2. Drugs and Schizophrenia-like Psychosis: 8. Substance-induced psychosis: an overview Jagadisha Thirthalli, Vivek Benegal and Bangalore N. Gangadhar
9. Stimulants and psychosis Nash N. Boutros, Matt Galloway and Eric M. Pihlgren
10. The psychotomimetic effects of PCP, LSD and Ecstasy: pharmacological models of schizophrenia? Vibeke S. Catts and Stanley V. Catts
11. Schizophrenia secondary to cannabis use Wayne Hall and Louisa Degenhardt
12. Toxic psychosis Rajeev Kumar and Jeffrey C. L. Looi
Section 3. Other Neurological Disorders: 13. Schizophrenia-like psychosis and traumatic brain injury (TBI) Perminder S. Sachdev
14. Cerebrovascular disease and psychosis Osvaldo P. Almeida and Sergio E. Starkstein
15. Neurodegenerative disorders (Alzheimer's disease, frontotemporal dementia) and schizophrenia-like psychosis Nicola T. Lautenschlager and Alexander F. Kurz
16. Storage disorders and psychosis Mark Walterfang and Dennis Velakoulis
17. Mitochondrial disorders and psychosis Dennis Velakoulis and Mark Walterfang
18. Psychosis associated with leukodystrophies Patricia I. Rosebush, Rebecca Anglin and Michael Mazurek
19. Normal pressure hydrocephalus Julian Trollor
20. Brain tumours Malcolm Hopwood and Lyn-May Lim
21. Demyelinating disease and psychosis Anthony Feinstein
Section 4. Systemic Disorders: 22. Infection and schizophrenia Alan S. Brown and Ezra S. Susser
Section 5. Genetic Disorders Related to SLP: 23. The status of genetic investigations of schizophrenia Bryan Mowry
24. Velocardiofacial Syndrome (Chromosome 22q11.2 Deletion Syndrome) as a model of schizophrenia Vandana Shashi and Margaret N. Berry
25. Psychosis in Prader-Willi Syndrome Stewart L. Einfeld, Sophie Kavanagh, Arabella Smith and Bruce J. Tonge
26. Friedrich's Ataxia and schizophrenia-type psychosis Perminder S. Sachdev
27. Wilson's disease Edward C. Lauterbach and Leslie Lester-Burns
28. Huntington's disease and related disorders and their association with schizophrenia-like psychosis Perminder S. Sachdev
29. Fahr's disease and psychosis Kim Burns and Henry Brodaty
Part IV. Related Concepts: 30. The Charles Bonnet Syndrome William Burke
31. Acute brief psychosis – an organic syndrome? Anand K. Pandurangi
Part V. Treatment: 32. Drug treatment of secondary schizophrenia Michael D. Jibson and Rajiv Tandon
33. Non-pharmacological interventions in secondary schizophrenia David J. Kavanagh, Jennifer M. Connolly and Kim T. Mueser.

Subject Areas: Clinical psychology [MMJ], Psychiatry [MMH], Neurology & clinical neurophysiology [MJN], Medical genetics [MFN]