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Salivary Diagnostics
David T. Wong (Edited by), D Wong (Author)
9780813813332, Wiley
Hardback, published 17 October 2008
320 pages
26.2 x 18.6 x 2.3 cm, 0.925 kg
Salivary Diagnostics surveys one of the most exciting areas of research in oral biology. Regarded as the mirror of the body, saliva has immense potential to yield real clinical improvements in our ability to diagnose, and hence treat, oral and systemic conditions. The composition of saliva and other oral fluids reflects the tissue fluid levels of therapeutic, hormonal, and immunological molecules, as well as the presence of markers for systemic and oral disease.
Contributors viii Foreword xv Preface xvii Acknowledgment xviii I Background and Foundation 1 Salivary Gland Development and Regeneration 3 2 Salivary Gland Physiology Relevant to Diagnostics 14 3 Saliva: Properties and Functions 27 4 Saliva Collectors 37 5 Salivary Secretion in Health and Disease 60 6 Processing and Storage of Saliva Samples 69 II Saliva Diagnostics 7 Historical Perspectives and Present 79 8 Diagnostics Other Than Blood 94 9 Perceptions of Saliva: Relevance to Clinical Diagnostics 104 10 Saliva-Based Diagnostic Technologies: Highlights of the NIDCR's Program 111 11 Human Salivary Proteomics 122 12 Genomic Targets in Saliva 129 13 Point-of-Care Diagnostics for Infectious diseases 136 14 Dental Caries Risk Assessment 150 15 Periodontal Disease 156 16 Role of Saliva in Detection of Substance Abuse 169 17 Head and Neck Cancer 180 18 Sjogren's Syndrome 189 19 Salivary Gland Dysfunction Associated with Systemic Disease 198 20 Progression and Treatment Evaluation in Diseases Affecting Salivary Glands 214 21 The Uses of Saliva in Forensic Genetics 226 22 SPKB—Salivary Proteome Knowledge Base: A Platform for Collaborative Proteomics Research 233 III Saliva Diagnostics—A New Industry 23 Commercialization of Oral Fluid Products and Technologies 243 24 Coverage and Reimbursement for Salivary Diagnostic Tests 255 25 Saliva Diagnostics in the Dentist's and Physician's Office 263 26 Salivary Hormones in Research and Diagnostics 270 27 Crossroads Between Saliva Diagnostics and Salivary Gland Gene Therapy 278 28 Saliva Diagnostics—A New Industry 288 Index 295
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Arjan Vissink, Andy Wolff, and Enno C.I. Veerman
Michael D. Turner and Jonathan A. Ship
Enno C.I. Veerman, Arjan Vissink, David T. Wong, and Arie van Nieuw Amerongen
Frank G. Oppenheim
Sudhir Srivastava and Karl Krueger
Sreenivas Koka and David T. Wong
Eleni Kousvelari, John T. McDevitt, Daniel Malamud, David T. Wong, and David R. Walt
Shen Hu, Markus Hardt, Susan J. Fisher, David T. Wong, John R. Yates, James E. Melvin, and Joseph A. Loo
Bernhard G. Zimmermann, Zhanzhi Hu, and David T. Wong
Paul L.A.M. Corstjens, Daniel Malamud
Paul C. Denny and Patricia A. Denny
Christoph A. Ramseier, Thiago Morelli, Janet S. Kinney, Meghan Dubois, Lindsay Rayburn, and William Giannobile
Uttam Garg and Lance Presley
Joseph A. Califano and Suhail K. Mithani
Philip C. Fox
Nelson L. Rhodus
Jiska M. Meijer, Cees G.M. Kallenberg, and Arjan Vissink
Jack Ballantyne and Jane Juusola
Weihong Yan, Weixia Yu, Shawn Than, Renli Qiao, D. Stott Parker, Joseph A. Loo, and David T. Wong
R. Sam Niedbala
James J. Crall
Chakwan Siew and Milton V. Marshall
Douglas A. Granger, Christine K. Fortunato, Leah C. Hibel
Bruce J. Baum, Ana P. Cotrim, Corinne M. Goldsmith, Fumi Mineshiba, Senrong Qi, Gabor Z. Racz, Yuval Samuni, Takayuki Sugito, Antonis Voutetakis, and Changyu Zheng
Stuart R. Smith, David T. Wong, and R. Michael Buch
Subject Areas: Other branches of medicine [MM]
