Reviews in Computational Chemistry, Volume 11

Kenny B. Lipkowitz (Edited by), KB Lipkowitz (Author), Donald B. Boyd (Edited by)

9780471192480, Wiley

Hardback, published 12 November 1997

431 pages
24.2 x 16.3 x 2.6 cm, 0.85 kg

Volume 11 Reviews in Computational Chemistry Kenny B. Lipkowitz and Donald B. Boyd The Theme of this Eleventh Volume is Computer-Aided Ligand Design and Modeling of Biomolecules. A Stellar Group of Scientists from Around the World Join in this Volume to Provide Tutorials for Beginners and Experts. Chapters 1 and 2 Take A Detailed Look at De Novo Design Methodologies for Discovering New Ligands which May Become Pharmaceuticals. Chapters 3 and 4 Cover the Methods and Applications of Three-Dimensional Quantitative Structure-Activity Relationships (3D-QSAR) Currently Used in Drug Discovery. Ways to Compute the Correct Lipophilic/Hydrophilic Behavior of Molecules are Taught in Chapter 5. Chapter 6 is an Exposition of Realistically Simulating DNA in the Complex Milieu of Ions that Surround it. An Appendix to this Volume Gives A Compendium of Software and Internet Tools for Computational Chemistry. -From Reviews of the Series . This Well-Respected Series Continues the Fine Selection of Topics and Presentation Qualities Set Forth by the Previous Members. For Example, Each Chapter Contains Thorough Treatment of the Theory Behind the Topic Being Covered. Moreover, the Background Material is Followed by Ample Timely Examples Culled From Recent Literature. Journal of Medicinal Chemistry

Recent Advances in Ligand Design Methods

Current Issues in De Novo Molecular Design

Theoretical and Practical Aspects of Three-Dimensional Quantitative Structure-Activity Relationships

Approaches to Three-Dimensional Quantitative Structure-Activity Relationships

Computational Approaches to Lipophilicity: Methods and Applications

Treatment of Counterions in Computer Simulations of DNA

Molecular Dynamics with General Holonomic Constraints and Application to Internal Co-ordinate Constraints

Appendix

Indexes.

Subject Areas: Chemistry [PN]