Reproductomics
The -Omics Revolution and Its Impact on Human Reproductive Medicine

Provides a thorough introduction to genomics and omics technologies as applied to human reproductive medicine, identifying specific genomic and molecular factors

José A. Horcajadas (Edited by), Jaime Gosálvez (Edited by)

9780128125717, Elsevier Science

Paperback, published 11 July 2018

425 pages
23.4 x 19 x 2.7 cm, 1.02 kg

Recent advances in genomic and omics analysis have triggered a revolution affecting nearly every field of medicine, including reproductive medicine, obstetrics, gynecology, andrology, and infertility treatment. Reproductomics: The –Omics Revolution and Its Impact on Human Reproductive Medicine demonstrates how various omics technologies are already aiding fertility specialists and clinicians in characterizing patients, counseling couples towards pregnancy success, informing embryo selection, and supporting many other positive outcomes. A diverse range of chapters from international experts examine the complex relationship between genomics, transcriptomics, proteomics, and metabolomics and their role in human reproduction, identifying molecular factors of clinical significance.

1. Is the classic spermiogram still informative? How did it develop and where is it going?
2. Genetics variations and male infertility
3. Genetic Variations and Male Infertility
4. Carrier Screening for Inherited Genetic Disorders: A Review of Current Practices
5. TELOMERES IN GERMLINE AND EARLY EMBRYO- AN OVERVIEW
6. Human Protamine Genes’ Polymorphisms As A Possible Cause Underlying Male Infertility
7. Small RNAs present in semen and their role in reproduction
8. ALTERED TRANSCRIPTOMIC PROFILES ASSOCIATED WITH MALE INFERTILITY
9. Proteomics and metabolomics studies and clinical outcomes
10. Epigenetics, spermatogenesis and male infertility
11. Changes in DNA methylation related to male infertility
12. Non-invasive methods of embryo selection
13. Genetic selection of the human embryos: from FISH to NGS, past and future
14. Unraveling the causes of failed fertilization after intracytoplasmic sperm injection due to oocyte activation deficiency
15. The molecular signature of the endometrial receptivity: research and clinical application
16. The acquisition of the human endometrial receptivity phenotype: lessons from proteomic studies
17. Stem Cell Derived Spermatozoa
18. Computational approaches in Reproductomics
19. Year 2020: The “-Omics? Technologies and Personalized Assisted Reproduction

Subject Areas: Endocrinology [MJG]