Reproductive Genetics

This book presents the findings of the RCOG Study Group findings on genetics underlying reproductive function.

Sean Kehoe (Edited by), Lyn Chitty (Edited by), Tessa Homfray (Edited by)

9781906985165, Royal College of Obstetricians and Gynaecologists (RCOG)

Paperback / softback, published 1 November 2009

242 pages
23.2 x 15.5 x 1 cm, 0.43 kg

Great progress has been made in genetics in recent years, with significant consequences for the field of reproductive genetics. The ability to identify genetic defects before implantation, to diagnose fetal abnormalities and to introduce screening programmes means that genetic testing now has a major role in preventive medicine. The 57th RCOG Study Group brought together a range of experts to examine the many clinical, ethical and societal issues around reproductive genetics. This book presents the findings of the Study Group, covering a range of disorders, advances in treatments and techniques, as well as the importance of educating the public and the potential ethical dilemmas that may arise as a result of new scientific findings and new methodologies.

1. Genetic aetiology of infertility Anu Bashamboo, Celia Ravel and Ken McElreavey
2. Disorders of sex development Lin Lin and John C. Achermann
3. Preimplantation genetic diagnosis: current practice and future possibilities Alison Lashwood and Tarek El-Toukhy
4. Ethical aspects of saviour siblings: procreative reasons and the treatment of children Mark Sheehan
5. Epigenetics, assisted reproductive technologies and growth restriction Jennifer M. Frost, Sayeda Abu-Amero, Caroline Daelemans and Gudrun E. Moore
6. Fetal stem cell therapy Jennifer Ryan, Michael Ting and Nicholas Fisk
7. Prenatal gene therapy Khalil Abi-Nader and Anna David
8. Ethical aspects of stem cell therapy and gene therapy S. Holm
9. Fetal dysmorphology: the role of the geneticist in the fetal medicine unit in targeting diagnostic tests Tessa Homfray
10. Fetal karyotyping: what should we be offering and how? John Crolla
11. Non-invasive prenatal diagnosis: the future of prenatal genetic diagnosis? Lyn Chitty, Gail Norbury and Helen White
12. Non-invasive prenatal diagnosis for fetal blood group status Geoff Daniels, Kirstin Finning, Peter Martin and Edwin Massey
13. Selective termination of pregnancy and preimplantation genetic diagnosis: some ethical issues in the interpretation of the legal criteria Rosamund Scott
14. Implementation and auditing of new genetics and tests: translating genetic tests into practice in the NHS Rob Elles and Ian Frayling
15. New advances in prenatal genetic testing: the parent perspective Jane Fisher
16. Informed consent: what should we be doing? Jenny Hewison and Louise Bryant
17. Consensus views arising from the 57th Study Group: Reproductive Genetics
Index.

Subject Areas: Gynaecology & obstetrics [MJT], Medical genetics [MFN], Public health & preventive medicine [MBN], Medicine [M]