Regulation of Downstream Targets

Edited by one of the best scientists in the field, this series presents the latest updates in the fields of protein chemistry and structural biology

Rossen Donev (Edited by)

9780443131813, Elsevier Science

Hardback, published 2 March 2023

456 pages
22.9 x 15.1 x 2.8 cm, 0.45 kg

Regulation of Downstream Targets, Volume 134 in the Advances in Protein Chemistry and Structural Biology series, presents interesting chapters on topics such as Transcriptional regulatory mechanisms and signaling networks in Viral Infections, Identification of potential key genes associated with pathogenesis and prognosis of endometrial cancer based on Integrated Bioinformatics Approaches, Differential regulation of genes in stage IB pancreatic cancer associated with increased risk of metastasis, AMPK-related LKB1-downstream targets, A compilation of bioinformatic approaches to identify novel downstream targets for the detection and prophylaxis of cancer, Protein phosphatases and their targets: Critical determinants of signaling pathway in plants, and more.

1. Transcriptional regulatory mechanisms and signaling networks in cancer
Chandrabose Selvaraj, Karthik Raja Ramalingam, Devadasan Velmurugan, and Sanjeev Kumar Singh
2. Identification of dysregulated canonical pathways associated with pathogenesis and progression of Amyotrophic Lateral Sclerosis—An integrated bioinformatics approach
Ankur Datta, S. Udhaya Kumar, Maria D'costa, Anusha Bothe, D. Thirumal Kumar, Hatem Zayed, and C. George Priya Doss
3. Elucidating the mechanism of antimicrobial resistance in Mycobacterium tuberculosis using gene interaction networks
Keerthana G., Karthick Vasudevan, Hrituraj Dey, Tasmia Kausar, S. Udhaya Kumar, D. Thirumal Kumar, Hatem Zayed, and C. George Priya Doss
4. AMPK-like proteins and their function in female reproduction and gynecologic cancer
Claire Baumgartner, Anil Kumar Yadav, and Ilana Chefetz
5. A compilation of bioinformatic approaches to identify novel downstream targets for the detection and prophylaxis of cancer
Mangala Hegde, Sosmitha Girisa, and Ajaikumar B. Kunnumakkara
6. Protein phosphatases and their targets: Comprehending the interactions in plant signaling pathways
Lokesh K. Saini, Malathi Bheri, and Girdhar K. Pandey
7. Calcium decoders and their targets: The holy alliance that regulate cellular responses in stress signaling
Barkha Ravi, Sibaji K. Sanyal, and Girdhar K. Pandey
8. Importin alpha family NAAT/IBB domain: Functions of a pleiotropic long chameleon sequence
Kazuya Jibiki, Takashi S. Kodama, and Noriko Yasuhara
9. AURORA KINASE A and related downstream molecules: A potential network for cancer therapy
Homa Fatma, and Hifzur R. Siddique
10. Emerging role of heat shock proteins in cardiovascular diseases
Joyita Hazra, Anupama Vijayakumar, and Nitish R. Mahapatra
11. Function, structure, evolution, regulation of a potent drug target, arylalkylamine N-acetyltransferase
Lei Zhang, Yu Tang, David J. Merkler, and Qian Han
12. Analysis of signaling cascades from myeloma cells treated with pristimerin
Heba Almaghrbi, Rehab Elkardawy, S. Udhaya Kumar, Shilpa Kuttikrishnan, Taghreed Abunada, Manoj Kumar Kashyap, Aamir Ahmad, Shahab Uddin, C. George Priya Doss, and Hatem Zayed
13. Mixed lineage kinase domain-like pseudokinase: Conventional (necroptosis) and unconventional (necroptosisindependent) functions and features
Tuna Onal, Melike Ozgul-Onal, and Ilana Chefetz

Subject Areas: Cellular biology [cytology PSF], Molecular biology [PSD], Biochemistry [PSB]