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Recent Trends in Carbohydrate Chemistry
Synthesis, Structure and Function of Carbohydrates
Presents the most recent methodologies in carbohydrate chemistry from an international team of experts
Amélia Pilar Rauter (Edited by), Bjørn E. Christensen (Edited by), László Somsák (Edited by), Paul Kosma (Edited by), Roberto Adamo (Edited by)
9780128174678, Elsevier Science
Paperback, published 29 April 2020
492 pages
22.9 x 15.1 x 3.1 cm, 0.77 kg
Carbohydrate chemistry provides access to carbohydrate-based natural products and synthetic molecules as useful biologically active structures relevant to many health care and disease-related biological processes. Recent Trends in Carbohydrate Chemistry: Synthesis, Structure, and Function of Carbohydrates covers green and sustainable reactions, organometallic carbohydrate chemistry, synthesis of glycomimetics, multicomponent reactions, and chemical transformations leading to molecular diversity based on carbohydrates. These include inhibitors of glycogen phosphorylase, which are relevant in controlling type 2 diabetes and sugar sulfates. Polysaccharides, which are commonly modified chemically, are also examined with contributions covering polysaccharide synthesis and modification of polysaccharides to obtain new structures and properties. Recent Trends in Carbohydrate Chemistry: Synthesis, Structure, and Function of Carbohydrates is ideal for researchers working as synthetic organic chemists, and for those interested in biomolecular chemistry, green chemistry, organometallic chemistry, and material chemistry in academia as well as in industry
I. Monosaccharide chemistry toward molecular diversity--Recent findings 1. Perspective on the transformation of carbohydrates under green and sustainable reaction conditions 2. Hydroxymethylfurfural (HMF) and Glucosyloxymethylfurfural (GMF) in Multi-Component Reactions 3. Alkynedicobalt complexes in carbohydrates: Synthetic applications 4. Molecular Diversity Through Gold-catalysis on Saccharide Building Blocks 5. Glycomimetics with unnatural glycosidic linkages 6. Synthetic Approaches to Functionalized Oxepanes and Azapanes from Monosaccharides 7. N- and C-Glycopyranosyl Heterocycles as Glycogen Phosphorylase Inhibitors 8. Recent developments in synthetic methods for sugar phosphates, phosphonates and analogous P-containing compounds II. Structure-function relationships in polysaccharides 16. Polysaccharides: chemical synthesis 17. Linear and cyclic amylose, beyond natural 18. Modification of xanthan in the ordered and disordered states 19. Derivatized polysaccharides on silica and hybridized with silica in chromatography and separation – a mini review
Subject Areas: Organic chemistry [PNN]
