Recent Advances in iPSC-Derived Cell Types

A timely and important collection of new information and applications, volume four addresses how the different niches maintain their own stem cells

Alexander Birbrair (Edited by)

9780128222300, Elsevier Science

Paperback, published 25 February 2021

282 pages, 60 illustrations (40 in full color)
23.4 x 19 x 1.9 cm, 0.59 kg

The series Advances in Stem Cell Biology is a timely and expansive collection of comprehensive information and new discoveries in the field of stem cell biology.Recent Advances in iPSC-derived Cell Types, Volume 4 addresses how different cell types can be derived from induced pluripotent stem cells.Somatic cells can be reprogrammed into Induced pluripotent stem cells by the expression of specific transcription factors. These cells are transforming biomedical research in the last 15 years. The volume teaches readers about current advances in the field. This book describes the use of induced pluripotent stem cells to form different cell types which can be used in cell therapy as well as to model several diseases in vitro, enabling us to study the cellular and molecular mechanisms involved in different pathologies. In recent years, remarkable progress has been made in the obtention of induced pluripotent stem cells and their differentiation into several cellular populations, tissues and organs using state-of-art techniques. This volume will cover what we know so far about the use of iPSCs to derive different cell types, such as: erythroid cells, mucosal-associated invariant T cells, megakaryocytes, cerebral cortical neurons, inner ear cell types, airway epithelial cells, male germ cells, trophoblasts, cardiomyocytes, ßpancreatic cells, and more. The volume is written for researchers and scientists interested in stem cell therapy, cell biology, regenerative medicine, and organ transplantation; and is contributed by world-renowned authors in the field.

1. iPSC-Derived Erythroid Cells
2. iPSC-Derived Mucosal-Associated Invariant T Cells
3. iPSC-Derived Megakaryocytes
4. From Human Pluripotent Stem Cells to Cerebral Cortical Ceurons
5. Differentiation of Inner Ear Cell Types from Human Induced Pluripotent Stem Cells for The Therapeutic Application in Sensorineural Hearing Loss
6. Application of Ips Cell-Derived Airway Epithelial Cells for Cell-Based Therapy and Disease Models
7. Male Germ Cell Derivation from iPSC
8. Cell Adhesion Restriction Induces Trophoblast Differentiation from Human Induced Pluripotent Stem Cells
9. Induced Pluripotent Stem Cell-Derived Cardiomyocytes: Generation and Enrichment Protocols, Immature and Mature Structure and Function
10. A Demanding Path from iPSC Towards Pancreatic ?- And ?-Cells

Subject Areas: Life sciences: general issues [PSA]