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Rapid Acting Antidepressants

Provides the authority and expertise of leading contributors who discuss advances in pharmacology

Ronald S. Duman (Volume editor), John H. Krystal (Volume editor)

9780128201893, Elsevier Science

Hardback, published 26 June 2020

402 pages
22.9 x 15.1 x 2.7 cm, 0.77 kg

The Advances in Pharmacology series presents a variety of chapters from the best authors in the field.

Part I – Neurobiology of ketamine effects

    1. Effects of ketamine and other rapidly acting antidepressants on hippocampal excitatory and inhibitory transmission
    2. Allie J. Widman and Lori L. McMahon

    3. Antidepressant mechanisms of ketamine: Focus on GABAergic inhibition
    4. Bernhard Luscher, Mengyang Feng and Sarah J. Jefferson

    5. The role of eEF2 kinase in the rapid antidepressant actions of ketamine
    6. Kanzo Suzuki and Lisa M. Monteggia

      Part II – The rapid therapeutic effects of ketamine

    7. Clinical overview of NMDA-R antagonists and clinical practice
    8. Pasha A. Davoudian and Samuel T. Wilkinson

    9. Ketamine for depression clinical issues
    10. Syed Z. Iqbal and Sanjay J. Mathew

    11. Chronic stress pathology and ketamine-induced alterations in functional connectivity in major depressive disorder: An abridged review of the clinical evidence
    12. Lynnette A. Averill, Samar Fouda, James W. Murrough and Chadi G. Abdallah

    13. Neurobiological biomarkers of response to ketamine
    14. Bashkim Kadriu, Elizabeth D. Ballard, Ioline D. Henter, Stephen Murata, Nimesha Gerlus and Carlos A. Zarate Jr

    15. Relapse prevention in treatment resistant major depressive disorder with rapid-acting antidepressants
    16. Jaskaran B. Singh, Maggie Fedgchin, Ella J. Daly and Wayne C. Drevets

    17. The emergence of ketamine as a novel treatment for posttraumatic stress disorder
    18. Adriana Feder, Sarah B. Rutter, Daniela Schille and Dennis S. Charney

      Part III – Novel rapid-acting antidepressant mechanisms related to ketamine

    19. mGlu2/3 receptor as a novel target for rapid acting antidepressants
    20. Shigeyuki Chaki

    21. Involvement of muscarinic receptor mechanisms in antidepressant drug action
    22. Jeffrey M. Witkin, Jodi L. Smith, Lalit K. Golani, Emily A. Brooks and Anna E. Martin

    23. The antidepressant efficacy of the muscarinic antagonist scopolamine: Past findings and future directions

Wayne C. Drevets, Anindya Bhattacharya and Maura L. Furey

Subject Areas: Pharmacology [MMG]

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