Purinergic Approaches in Experimental Therapeutics

Kenneth A. Jacobson (Edited by), KA Jacobson (Author), Michael F. Jarvis (Edited by)

9780471140719, Wiley

Hardback, published 23 July 1997

581 pages
24.1 x 16.7 x 3.2 cm, 1.021 kg

International renommierte Autoren bringen Ihnen alle wichtigen therapeutischen Anwendungen purinerger Rezeptoren nahe und stellen die aktuellsten Entwicklungen dieses relativ jungen Forschungsgebietes dar. Neben Details zur molekularen Pharmakologie und medizinischen Chemie finden Sie Beiträge zu therapeutischen Implikationen in Kardiologie, Stoffwechsel, Immunologie, Neurologie und Krebstherapie.

Partial table of contents:

HISTORICAL PERSPECTIVE.

Purinergic Neurotransmission and Neuromodulation: A HistoricalPerspective (M. Williams & G. Burnstock).

MOLECULAR PHARMACOLOGY.

Adenosine Receptor Subtypes: New Insights From Cloning andFunctional Studies (G. Stiles).

MEDICINAL CHEMISTRY.

Development of Selective Purinoceptor Agonists and Antagonists (K.Jacobson & A. van Rhee).

THERAPEUTIC IMPLICATIONS.

Cardiac Electrophysiology of Adenosine: Antiarrhythmic andProarrhythmic Actions (L. Belardinelli, et al.).

The Role of Adenosine in Asthma (M. Jacobson and T. Bai).

Psychomotor Aspects of Adenosine Receptor Activation (M.Jarvis).

Adenosine Effects in Sleep Apnea (D. Carley & M.Radulovacki).

ATP in the Treatment of Cancer (E. Rapaport).

Index.

Subject Areas: Other branches of medicine [MM]