Psychostimulants

A volume that explores the physiological, behavioral and neurobiological study of psychostimulant addiction

George F. Koob (Author), Michael A. Arends (Author), Mandy L McCracken (Author), Michel Le Moal (Author)

9780128169902, Elsevier Science

Paperback, published 12 May 2020

262 pages
23.4 x 19 x 1.7 cm, 0.57 kg

"This book is very technical and not geared to the average reader. It reviews the increased understanding of biological underpinnings of addiction and how, in some individuals, neurocircuitry is affected by psychostimulants, leading to their pathological use. Those who are involved or interested in the neurobiological underpinnings of addiction will find this a useful data update. These scientific understandings are also important for clinicians in the field to create a paradigm shift in their understanding of what drives these diseases." --Doody

A current survey and synthesis of the most important findings in our understanding of the neurobiological mechanisms of addiction are detailed in our Neurobiology of Addiction series, each volume addressing a specific area of addiction. Psychostimulants, Volume 2 in the series, explores the molecular and cellular systems in the brain responsible for psychostimulant addiction, including both direct/indirect sympathomimetics and nonsympathomimetics. This volume introduces the readers to the history of psychostimulant use. The authors clearly differentiate the neurobiological effects into three distinct stages of the addiction cycle: binge/intoxication, withdrawal/negative affect, and preoccupation/anticipation.

1. Definitions2. History of psychostimulant use 3. Physiological effects4. Behavioral effects 5. Pharmacokinetics6. Behavioral mechanism of action 7. Medical use, abuse, and addiction 8. Neurobiological effects 9. Summary

Subject Areas: Neurosciences [PSAN], Physiological & neuro-psychology, biopsychology [JMM]