Protein Kinases in Development and Disease

Reviews current knowledge of the developmental functions of both well and lesser known kinases

Andreas Jenny (Volume editor)

9780128015131

Hardback, published 22 February 2017

498 pages
22.9 x 15.1 x 3 cm, 0.97 kg

Protein Kinases in Development and Disease discusses and reviews important, but often neglected, kinases. A good representation of current model organisms from plants and C. elegans to mice are used as the basis to illustrate how we can use our understanding of normal development to learn about disease.

1. WNK Kinases in Development and Disease 2. SGK1: The Dark Side of PI3K Signaling 3. Homeodomain-Interacting Protein Kinases: Diverse and Complex Roles in Development and Disease 4. ROR-Family Receptor Tyrosine Kinases 5. Regulation of Drosophila Development by the Golgi Kinase Four-Jointed 6. The Hippo Pathway: A Master Regulatory Network Important in Development and Dysregulated in Disease 7. Regulation of Embryonic and Postnatal Development by the CSF-1 Receptor 8. Glycogen Synthase Kinase 3: A Kinase for All Pathways? 9. CK1 in Developmental Signaling: Hedgehog and Wnt 10. Ligand Receptor-Mediated Regulation of Growth in Plants 11. Regulation of Cell Polarity by PAR-1/MARK Kinase 12. Receptor Tyrosine Kinases and Phosphatases in Neuronal Wiring: Insights From Drosophila 13. VEGF Receptor Tyrosine Kinases: Key Regulators of Vascular Function

Subject Areas: Molecular biology [PSD], Developmental biology [PSC]