Protein Design and Structure

Edited by one of the best scientists in the field, this series presents the latest updates in the field of protein chemistry and structural biology

Rossen Donev (Edited by)

9780323992299, Elsevier Science

Hardback, published 27 April 2022

432 pages
22.9 x 15.1 x 2.8 cm, 0.84 kg

Protein Design and Structure, Volume 130 in the Advances in Protein Chemistry and Structural Biology series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

1. Algorithms for protein design
Sekhar Talluri
2. Computational prediction of protein functional sites—Applications in biotechnology and biomedicine
Florencio Pazos
3. Structure and chemistry of enzymatic active sites that play a role in the switch and conformation mechanism
Chandrabose Selvaraj, Ondipilliraja Rudhra, Abdulaziz S. Alothaim, Mustfa Alkhanani, and Sanjeev Kumar Singh
4. Accelerating therapeutic protein design
Mohammad ElGamacy
5. Aromatic interactions directing peptide nano-assembly
Sajitha Sasidharan and Vibin Ramakrishnan
6. Understanding binding affinity and specificity of modular protein domains: A focus in ligand design for the polyproline-binding families
Jose C. Martinez, Francisco Castillo, Javier Ruiz-Sanz, Javier Murciano-Calles, Ana Camara-Artigas, and Irene Luque
7. The structural basis of histone modifying enzyme specificity and promiscuity: Implications for metabolic regulation and drug design
Tim J. Kamerzell, Brittney Mikell, Lei Chen, Harold Elias, Buddhadeb Dawn, Calum MacRae, and C. Russell Middaugh
8. Designing synthetic transcription factors: A structural perspective
Aparna Boral, Madhurima Khamaru, and Devrani Mitra
9. Recent advances in structural studies of 14-3-3 protein complexes
Nikolai N. Sluchanko
10. Immunosafe(r)-by-design nanoparticles: Molecular targets and cell signaling pathways in a next-generation model proxy for humans
Annalisa Pinsino and Maria Di Bernardo
11. Mutations in G6PC2 gene with increased risk for development of type 2 diabetes: Understanding via computational approach
S. Udhaya Kumar, Balu Kamaraj, Rinku Polachirakkal Varghese, V. Anu Preethi, R. Bithia, and C. George Priya Doss
12. Computational structural assessment of BReast CAncer type 1 susceptibility protein (BRCA1) and BRCA1-Associated Ring Domain protein 1 (BARD1) mutations on the protein-protein interface
D. Thirumal Kumar, S. Udhaya Kumar, Nikita Jain, Baviri Sowmya, Kamakshi Balsekar, R. Siva, Balu Kamaraj, Mariem Sidenna, C. George Priya Doss, and Hatem Zayed
13. Evolutionary aspect of Miltefosine transporter proteins in Leishmania major
Ritika Kabra and Shailza Singh

Subject Areas: Cellular biology [cytology PSF], Molecular biology [PSD], Biochemistry [PSB], DNA & Genome [PSAK1]