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Prokaryotic Metabolism and Physiology

Extensive and up-to-date review of key metabolic processes in bacteria and archaea and how metabolism is regulated under various conditions.

Byung Hong Kim (Author), Geoffrey Michael Gadd (Author)

9781316622919, Cambridge University Press

Paperback / softback, published 16 May 2019

504 pages, 373 b/w illus. 60 tables
24.6 x 18.8 x 2.3 cm, 1.1 kg

'Overall this is an excellent text for researchers to refer to and for more advanced students to understand the complexities that are presented by prokaryotic organisms.' Ellis O'Neill, The Biologist

Vast numbers of different prokaryotic microorganisms shape the biosphere, with diverse metabolic capabilities. Determination of genome sequences for a wide range of bacteria and archaea now requires an in-depth knowledge of prokaryotic metabolic function to give biochemical, physiological and ecological meaning to the genomic information. This new edition describes up-to-date knowledge of the key metabolic processes that occur under different conditions, and the cellular processes that determine prokaryotic roles in the environment, biotechnology and human health. Essential for students of microbiology, applied microbiology, biotechnology, genomics and systems biology, this advanced textbook covers prokaryotic structure, composition, nutrient transport, biosynthesis and growth. Newly characterised metabolic pathways are included, as well as the latest understanding of metabolic regulation and stress responses. Additionally, the link between energetics, growth and survival is discussed as well as the maintenance of genetic integrity by the bacterial immune system.

1. Introduction to bacterial physiology and metabolism
2. Composition and structure of prokaryotic cells
3. Membrane transport – nutrient uptake and protein excretion
4. Glycolysis
5. Tricarboxylic acid (TCA) cycle, electron transport and oxidative phosphorylation
6. Biosynthesis and growth
7. Heterotrophic metabolism on substrates other than glucose
8. Anaerobic fermentation
9. Anaerobic respiration
10. Chemolithotrophy
11. Photosynthesis
12. Metabolic regulation
13. Energy, environment and microbial survival.

Subject Areas: Bacteriology [non-medical PSGD], Microbiology [non-medical PSG], Biochemical immunology [PSBM], Genetics [non-medical PSAK], Immunology [MJCM], Cellular physiology [MFGC]

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