Progress in Medicinal Chemistry

Contains eclectic developments in medicinal chemistry, with authoritative reviews of targets and technologies that address new therapeutics

David R. Witty (Series edited by), Brian Cox (Series edited by)

9780444642776, Elsevier Science

Hardback, published 18 March 2019

197 pages
22.9 x 15.1 x 1.9 cm, 0.47 kg

Progress in Medicinal Chemistry, Volume 58, provides a review of eclectic developments in medicinal chemistry, with each chapter written by an international board of authors. Topics covered in this new release include Amyotrophic lateral sclerosis (ALS), Covalent-binding Drugs, Natural Product Drug Delivery – A Special Challenge?, and SMN2 gene splicing modifier, and more.

1. Covalent binders in drug discovery Maria A. Argiriadi, Aleksandra Baranczak, Michael M. Friedman, Julia Gavrilyuk, Adrian D. Hobson, Jonathan J. Hulce, Sami Osman, Noel S. Wilson and Anil Vasudevan 2. Amyotrophic lateral sclerosis Klara Valko and Lukasz Ciesla 3. Rewriting the (tran)script: Application to spinal muscular atrophy Hasane Ratni, Lutz Mueller and Martin Ebeling 4. Natural product drug delivery: A special challenge? Neil J. Press, Emilie Joly and Peter Ertl

Subject Areas: Organic chemistry [PNN], Pharmacology [MMG]