Progress in Medicinal Chemistry

A review of eclectic developments in medicinal chemistry, with authoritative extended reviews of targets and technologies addressing new therapeutics

G. Lawton (Series edited by), David R. Witty (Series edited by)

9780444637154, Elsevier Science

Hardback, published 1 February 2016

260 pages
22.9 x 15.1 x 2.2 cm, 0.26 kg

Progress in Medicinal Chemistry provides a review of eclectic developments in medicinal chemistry. This volume includes chapters covering recent advances in cancer therapeutics, fluorine in medicinal chemistry, a perspective on the next generation of antibacterial agents derived by manipulation of natural products, a new era for Chagas Disease drug discovery? and imaging in drug development.

1. Non-Systemic Intestine-Targeted DrugsMatthew C. T. Fyfe2. Measurement, Interpretation and Use of Free Ligand Solution Conformations in Drug DiscoveryThorsten Nowak, Martin Watson and Charles D. Blundell3. Recent Advances in the Discovery of Deubiquitinating Enzyme InhibitorsMark Kemp4. The Evolving Role of the Medicinal ChemistGeoff Lawton and Peter Nussbaumer

Subject Areas: Organic chemistry [PNN], Pharmacology [MMG]