Progress in Medicinal Chemistry

A highly valuable reference for medicinal chemists, biologists, doctors, and pharmacists

F.D. King (Edited by), G. Lawton (Edited by)

9780444528087, Elsevier Science

Hardback, published 19 February 2007

232 pages
27.9 x 21 x 2.1 cm, 0.42 kg

The success of any drug discovery project relies upon the quality of the lead that initiates the lead optimization process. What defines a ‘quality lead’, where these ‘quality leads’ come from and how one discovers them has been the subject of intense debate within the pharmaceutical industry, relies upon defining those properties that historically have led to successful drug discovery. This volume addresses these questions and specifically discusses diabetes, obesity and tuberculosis.

Preface
List of Contributors
Hit and Lead Identification: Efficient practices for drug discovery
DPPIV Inhibition: Promising Therapy for the Treatment of Type 2 Diabetes
Recent Progress Towards Nonpeptide Ligands for the Melanocortin-4 Receptor
Tuberculosis chemotherapy: recent developments and future perspectives
Subject Index
Author Index (Volumes 1-45)
Subject Index (Volumes 1-45)

Subject Areas: Pharmaceutical technology [TDCW], Organic chemistry [PNN], Pharmacology [MMG]