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Principles of Translational Science in Medicine
From Bench to Bedside
The principles, tools, and algorithms of translational science in medicine, plus an update on major achievements in translating research into medically relevant therapies
Martin Wehling (Edited by)
9780128006870
Hardback, published 9 April 2015
364 pages
27.6 x 21.5 x 2.5 cm, 1.29 kg
"This is an easy to read resource for biomedical scientists interested in the current and evolving approach to integrating various scientific approaches to answer questions important for the diagnosis and treatment of human disease. Score: 86 - 3 Stars" --Doody's
Principles of Translational Science in Medicine: From Bench to Bedside, Second Edition, provides an update on major achievements in the translation of research into medically relevant results and therapeutics. The book presents a thorough discussion of biomarkers, early human trials, and networking models, and includes institutional and industrial support systems. It also covers algorithms that have influenced all major areas of biomedical research in recent years, resulting in an increasing numbers of new chemical/biological entities (NCEs or NBEs) as shown in FDA statistics. The book is ideal for use as a guide for biomedical scientists to establish a systematic approach to translational medicine.
1. Introduction and Definitions 2. What Is Translational Medicine? 3. Tools 4. Biomarkers 5. Early Clinical Trial Design 6. Pharmaceutical Toxicology 7. Translational Science Biostatistics 8. Intellectual Property Rights in Translation 9. Translational research in the Elderly 10.The View of Big Pharma 11. Translational Science in Medicine: Putting the Pieces Together 12. Biomarkers, Early Human Trials, Networking, Translatability Assessment 13. Learning by Experience: Examples of Translational Processes in the Cardiovascular Field
Subject Areas: Life sciences: general issues [PSA], Pharmacology [MMG], Clinical & internal medicine [MJ], Medical research [MBGR]
