Principles and Applications of Molecular Diagnostics

A comprehensive guide for clinical chemists, laboratory genomics specialists, and biologists applying molecular technology to clinical diagnosis, derived from the sixth edition of the bestselling Tietz Textbook of Clinical Chemistry and Molecular Diagnostics

Nader Rifai (Edited by), A. Rita Horvath (Edited by), Carl T. Wittwer (Edited by), Jason Park (Edited by)

9780128160619, Elsevier Science

Paperback, published 18 June 2018

422 pages
27.6 x 21.5 x 2.7 cm, 1.25 kg

Principles and Applications of Molecular Diagnostics serves as a comprehensive guide for clinical laboratory professionals applying molecular technology to clinical diagnosis. The first half of the book covers principles and analytical concepts in molecular diagnostics such as genomes and variants, nucleic acids isolation and amplification methods, and measurement techniques, circulating tumor cells, and plasma DNA; the second half presents clinical applications of molecular diagnostics in genetic disease, infectious disease, hematopoietic malignancies, solid tumors, prenatal diagnosis, pharmacogenetics, and identity testing. A thorough yet succinct guide to using molecular testing technology, Principles and Applications of Molecular Diagnostics is an essential resource for laboratory professionals, biologists, chemists, pharmaceutical and biotech researchers, and manufacturers of molecular diagnostics kits and instruments.

1. Principles of molecular biology 2. Genomes and variants 3. Nucleic acid isolation 4. Nucleic acid techniques 5. Molecular microbiology 6. Genetics 7. Solid tumor genomics 8. Genetic aspects of hematopoietic malignancies 9. Circulating tumor cells 10. Circulating nucleic acids for prenatal diagnostics 11. Pharmacogenetics 12. Identity testing

Subject Areas: Analytical chemistry [PNF]