Principles and Applications of Asymmetric Synthesis

Guo-Qiang Lin (Author), Yue-Ming Li (Author), Albert S. C. Chan (Author)

9780471400271, Wiley

Hardback, published 23 January 2001

536 pages
24.4 x 16.1 x 3.2 cm, 0.921 kg

"Lin and colleagues...consolidate and evaluate the most useful methodologies for producing enantiomerically pure or enriched compounds." (SciTech Book News, Vol. 25, No. 3, September 2001)

"...a concise and fairly comprehensive overview..." (Angewandte Chemie, 15 October 2001)

"...this book is worthy of purchase for library collections and for chemists who would like to have a one-volume summary of the last 20 years of asymmetric synthesis. Those actively involved in asymmetric synthesis research will find this book most useful..." (Journal of Natural Products, Vol. 64, 2001)

"...a very good review of basic asymmetric methodology that can be recommended to students of organic chemistry..." (Journal of Medicinal Chemistry, Vol. 44, No. 26 2001)

"a well balanced survey of stereocontrolled methodologies and synthetic applications from which the reader can achieve valuable information." (ChemWeb, 14 January 2002)

"This book is quite readable and is highly recommended for those clinicians and administrators who want or need a practical and time-effective way to approach assessment, treatment planning and outcome measurement." (Keith Harris, Ph.D., clinical psychologist and supervisor of Victor Valley Behavioral Health Center, San Bernardino, California).

"There are many books on asymmetric synthesis, but this work...is one of the most useful and comprehensive" (Organic Process Research & Development)

Wer enantiomerenrein oder wenigstens -angereichert synthetisieren will, kommt (insbesondere in der Pharmazie) an der asymmetrischen Synthese kaum vorbei. International angesehene Experten stellten in diesem Band die wichtigsten heute bekannten stochiometrischen und katalytischen asymmetrischen Prozesse zusammen. Uber 450 Reaktionen werden besprochen - kein anderes Buch zum Thema bietet momentan ein derart breites Spektrum. (01/01)

Preface.

Abbreviations.

Introduction.

-Alkylation and Catalytic Alkylation of Carbonyl Compounds.

Aldol and Related Reactions.

Asymmetric Oxidations.

Asymmetric Diels-Alder and Other Cyclization Reactions.

Asymmetric Catalytic Hydrogenation and Other Reduction Reactions.

Applications of Asymmetric Reactions in the Synthesis of Natural Products.

Enzymatic Reactions and Miscellaneous Asymmetic Syntheses.

Index.

Subject Areas: Chemistry [PN]