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Prebiotics and Probiotics in Human Milk
Origins and Functions of Milk-Borne Oligosaccharides and Bacteria
Through a presentation of state-of-the-science information on the origins and functions of human milk oligosaccharides and bacteria, this book demonstrates the important relationship between them
Michelle McGuire (Edited by), Mark A McGuire (Edited by), Lars Bode (Edited by)
9780128027257
Hardback, published 1 November 2016
506 pages
23.4 x 19 x 3 cm, 1.22 kg
Prebiotics and Probiotics in Human Milk: Origins and Functions of Milk-Borne Oligosaccharides and Bacteria provides a comprehensive, yet approachable, treatise on what is currently known about the origins and functions of human milk oligosaccharides (HMO), the complex sugars in milk that are not digested by the infant. The book examines how HMOs and bacteria in human milk may function independently and coordinately to influence both maternal and infant health. Human milk is the only food “designed? specifically to nourish humans, indeed representing the essence of a perfect “functional food.? And although researchers have been studying its composition for decades, surprisingly little is really understood about the origins and functions of its myriad components, an area that is especially true for HMOs and bacteria. This book provides a thorough review of the newest research on these inter-related milk constituents as written by a team of experts from both academia and industry who actively conduct HMO and human milk microbiome research as they endeavor to apply this new knowledge to infant nutrition. Each chapter provides objective rationale for what research is still needed in this rapidly evolving area, also discussing the challenges and opportunities faced by the industry in adding HMO and microbes to infant food products. This book is a valuable resource for nutrition researchers focused on infant nutrition, food scientists and product developers working on infant formula, and clinicians interested in broadening their understanding of the benefits of human milk for infants.
Section A. Background, Structures, Synthesis, and Analysis Chapter 1. From Bifidus Factor to Human Milk Oligosaccharides: A Historical Perspective on Complex Sugars in Milk Chapter 2. Structures, Classification, and Biosynthesis of Human Milk Oligosaccharides Chapter 3. Oligosaccharides in the Milk of Other Mammals Chapter 4. Analytical Methods to Characterize Human Milk Oligosaccharides Section B. Potential Functions and Benefits Chapter 5. Oligosaccharide Metabolism in the Breastfed Infant Chapter 6. The Role of Human Milk Oligosaccharides in Host–Microbial Interactions Chapter 7. Potential Public Health Impact of Human Milk Oligosaccharides Chapter 8. Human Milk Oligosaccharides as Modulators of Intestinal and Systemic Immunity Section C. Challenges and Opportunities Chapter 9. Making Human Milk Oligosaccharides Available for Research and Application – Approaches, Challenges, and Future Opportunities Section D. Background, Methods, Origin, and Interpretation Chapter 10. Isn’t Milk Sterile? A Historical Perspective on Microbes in Milk Chapter 11. From the Human Milk Microbiota to the Human Milk Metagenome: Evolution of Methods to Study Human Milk Microbial Communities Chapter 12. Maternal Factors Related to Variability in the Human Milk Microbiome Chapter 13. The Origin of Human Milk Bacteria Section E. Human Milk Microbes and Health Chapter 14. An Evolutionary, Biosocial Perspective on Variation in Human Milk Microbes and Oligosaccharides: An Example of Eco-Homeorhesis? Chapter 15. Infectious Mastitis During Lactation: A Mammary Dysbiosis Model Chapter 16. Probiotics During the Perinatal Period: Impact on the Health of Mothers and Infants Section F. Challenges and Opportunities Chapter 17. Human Milk Microbes – Summary and Research Gaps
Subject Areas: Fitness & diet [VFM], Food & beverage technology [TDCT]
