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Practical Transfusion Medicine
Michael F. Murphy (Edited by), David J. Roberts (Edited by), Mark H. Yazer (Edited by), Nancy M. Dunbar (Edited by)
9781119665816, Wiley
Hardback, published 18 August 2022
672 pages
25.4 x 18.8 x 3.1 cm, 1.406 kg
Practical Transfusion Medicine Practical Transfusion Medicine, Sixth Edition The pace of change in transfusion medicine is relentless, with new scientific and technological developments and continuing efforts to improve transfusion practice. This sixth edition of Practical Transfusion Medicine has been updated significantly to reflect the rapid changes in transfusion medicine since the fifth edition was published in 2017. The primary purpose of this edition remains the same as the first: to provide a comprehensive guide to transfusion medicine. This book contains more depth of information than standard handbooks on transfusion medicine, whilst being more concise and approachable than a standard reference text. This book covers the principles of transfusion medicine, the complications of transfusion, practice in blood centres and hospitals and clinical transfusion practice. This sixth edition includes a new section on patient blood management, cellular and tissue therapy, organ transplantation and the development of the evidence base for transfusion. It also features a new chapter on transfusion-associated circulatory overload to underline its importance as a complication of transfusion, and a reconfiguration of the section on clinical transfusion practice to allow consideration of the transfusion management of medical, surgical and haematology patients with and without bleeding. This sixth edition of Practical Transfusion Medicine provides accessible and comprehensive coverage of the field of transfusion medicine. It is a standalone text that will be useful to clinical and scientific staff: not only for trainees who require an overview of the field, but also for established practitioners who are involved in some aspect of transfusion medicine and require a comprehensive, accessible reference book.
List of Contributors ix Preface to the Sixth Edition xvi 1 Introduction: Two Centuries of Progress in Transfusion Medicine 1 Part I Basic Principles of Immunohaematology 11 2 Essential Immunology for Transfusion Medicine 11 3 Human Blood Group Systems 21 4 Human Leukocyte Antigens 33 5 Platelet and Neutrophil Antigens 47 6 Pretransfusion Testing and the Selection of Red Cell Products for Transfusion 64 Part II Complications of Transfusions 77 7 Investigation of Acute Transfusion Reactions 77 8 Haemolytic Transfusion Reactions 91 9 Febrile and Allergic Transfusion Reactions 108 10 Transfusion- Associated Circulatory Overload 120 11 Transfusion- Related Acute Lung Injury (TRALI) 130 12 Purported Adverse Effects of ‘Old Blood’ 145 13 Transfusion- Induced Immunomodulation 154 14 Transfusion- Associated Graft- versus- Host Disease and Microchimerism 166 15 Posttransfusion Purpura 181 16 Heparin- Induced Thrombocytopenia 187 17 Transfusion- Transmitted Infections 206 18 Bacterial Contamination 221 19 Emerging Infections and Transfusion Safety 229 Part III Practice in Blood Centres and Hospitals 238 20 Regulatory Aspects of Blood Transfusion 238 21 The Role of Hemovigilance in Transfusion Safety 247 22 Donors and Blood Collection 257 23 Blood Donation Testing and the Safety of the Blood Supply 269 24 Production and Storage of Blood Components 278 25 Blood Transfusion in Hospitals 290 26 Disaster Preparedness 313 27 Blood Transfusion in a Global Context 324 Part IV Clinical Transfusion Practice 337 28 Inherited and Acquired Disorders of Haemostasis 337 29 Point- of- Care Haemostasis Testing 353 30 Transfusion in Bleeding Patients 365 31 Transfusion in Non- Bleeding Medical and Surgical Patients 374 32 Transfusion in Malignant Haematological Disease 385 33 Transfusion in Benign Haematological Disease 399 34 Transfusion in Patients with Haemoglobinopathies 409 35 Transfusing Neonates and Infants 417 36 Immunodeficiency and Immunoglobulin Therapy 426 Part V Patient Blood Management 441 37 Development of a Patient Blood Management Programme 441 38 Perioperative Patient Blood Management 451 39 Restrictive Transfusion Practice and How to Implement It 465 40 Using Data to Support Patient Blood Management 476 Part VI Cellular Therapy and Transplantation 489 41 Regulation and Accreditation in Cellular Therapy 489 42 Stem Cell Collection and Therapeutic Apheresis 504 43 Haemopoietic Stem Cell Processing and Storage 519 44 Haematopoietic Cell Transplantation 531 45 CAR- T Cells and Recent Advances in Clinical Cellular Immunotherapy 543 46 Tissue Banking 554 Part VII Development of the Evidence Base for Transfusion 561 47 Observational and Interventional Trials in Transfusion Medicine 561 48 Getting the Most Out of the Evidence for Transfusion Medicine and Lessons from the COVID- 19 Pandemic 576 49 A Primer on Biostatistics 590 50 A Primer on Health Economics 609 51 Scanning the Future of Transfusion Medicine 620 Index 632
Walter H. (Sunny) Dzik and Michael F. Murphy
Gregory A. Denomme
Geoff Daniels and Sean Stowell
H. Cliff Sullivan and Caroline R. Alquist
Brian R. Curtis
Mark H. Yazer, Meghan Delaney and Gregory A. Denomme Copyrighted Material
Heather Leary, Kathryn E. Webert and Nancy M. Heddle
Edwin J. Massey, Robertson D. Davenport and Richard M. Kaufman
Sarah K. Harm and Mark K. Fung
Robert B. Klanderman and Alexander P.J. Vlaar
Alexander P.J. Vlaar and Rick Kapur
Lirong Qu and Darrell J. Triulzi
Neil Blumberg, Majed A. Refaai and Joanna M. Heal
Alexandra Budhai, Richard O. Francis and Beth H. Shaz
Michael F. Murphy
Theodore E. Warkentin and Andreas Greinacher
Steven J. Drews and Roger Y. Dodd
Sandra Ramírez- Arcos and Mindy Goldman
Roger Y. Dodd
Louis M. Katz, Peter Flanagan and William G. Murphy
Katharine A. Downes and Barbee I. Whitaker
Marc Germain and Pierre Tiberghien
Mindy Goldman and Steven J. Drews
Marissa Li, Rebecca Cardigan, Stephen Thomas and Ralph Vassallo
Zoe K. McQuilten, Erica M. Wood, Mark H. Yazer and Michael F. Murphy
Heidi Doughty, Fateha Chowdhury and Richard Rackham
David J. Roberts, Imelda Bates, Stephen P. Field, Aggrey Dhabangi, Jean Pierre Allain and Meghan Delaney
Irina Chibisov, Jansen Seheult and Franklin Bontempo
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Jonathan H. Waters
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Julia Wolf, Zbigniew (Ziggy) M. Szczepiorkowski and James Griffin
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Jay E. Menitove, Paul M. Ness, Suzanne R. Thibodeaux and Edward L. Snyder
Subject Areas: Clinical & internal medicine [MJ]
