Polycomb Group Proteins

A comprehensive reference that provides key insights for scientists, health care professionals, and advanced students interested in the epigenetic process

Vincenzo Pirrotta (Author)

9780128097373

Hardback, published 5 January 2017

372 pages
22.9 x 15.1 x 2.5 cm, 0.77 kg

Approx.354 pages

1. Introduction to Polycomb Group Mechanisms2. The Role of RAWUL and SAM in Polycomb Repression Complex 1 Assembly and Function3. The Chromodomain of Polycomb: Methylation Reader and Beyond4. Unraveling the Roles of Canonical and Noncanonical PRC1 Complexes5. Structure and Biochemistry of the Polycomb Repressive Complex 1 Ubiquitin Ligase Module6. Cooperative Recruitment of Polycomb Complexes by Polycomb Response Elements7. Polycomb Function and Nuclear Organization8. Molecular Architecture of the Polycomb Repressive Complex 29. Polycomb Repressive Complex 2 Structure and Function10. Regulation of PRC2 Activity11. Activating Mutations of the EZH2 Histone Methyltransferase in Cancer12. PcG Proteins in Caenorhabditis elegans13. Global Functions of PRC2 Complexes

Subject Areas: Insects [entomology PSVT7], Molecular biology [PSD], DNA & Genome [PSAK1]