Platelets in Hematologic and Cardiovascular Disorders
A Clinical Handbook

Completely new text on platelets in all haematologic, cardiovascular and allergic disorders; a practical resource for all clinicians.

Paolo Gresele (Edited by), Valentin Fuster (Edited by), Jose A. Lopez (Edited by), Clive P. Page (Edited by), Jos Vermylen (Edited by)

9780521881159, Cambridge University Press

Hardback, published 13 December 2007

526 pages, 50 tables
25.2 x 19.8 x 3 cm, 1.408 kg

'This book actually is not simply an updated version of the previous, excellent, book by the same Editors … but represents a completely new book with several important conceptual and organisational changes. … The Editors are all involved in studies on platelets at the highest level and coming from different disciplines (Internal Medicine, Pharmacology, Cardiology, Haematology) provide different angles to the subject of the book. The book is handy and well published, with coloured pages and clearly marked tables, headings and subheadings which makes it easy to consult and remember. … Overall this is an excellent handbook that provides a wide range of informations in a complete and clear, but concise, way that will serve as a comprehensive and authoritative guide to the diagnosis and therapeutics of diseases involving platelets. AN interesting additional bonus is the accessibility of additional illustrative and textual materials that can be found at http://www.cambridge.org/gresele.' Internal and Emergency Medicine

A rapid increase in our understanding of the biology of platelets and their role in disease in recent years has been paralleled by increasing successes with established platelet-modifying therapies in many clinical conditions. This text focuses on the clinical role of platelets in a wide variety of haematologic, cardiovascular and other disorders, providing a practical, clinically relevant handbook for all clinicians and researchers interested in platelets and their role in disease. Covering platelet physiology, bleeding disorders, thrombotic disorders and antithrombotic therapy. Chapters cover all the conventional and less conventional aspects of platelet involvement in disease, with an emphasis on recent clinical developments. Clear take home messages have been included in each chapter to aid clinical practice. With contributions from leading experts across three continents, Platelets in Hematologic and Cardiovascular Disorders is an up-to-date, well illustrated, practical resource for everyone involved in clinical practice with platelet disorders.

Preface
1. The structure and production of blood platelets Joseph E. Italiano, Jr
2. Platelet immunology: structure, functions and polymorphisms of membrane glycoproteins Yasuo Ikeda, Yumiko Matsubara and Tetsuji Kamata
3. Mechanisms of platelet activation Lawrence Brass and Timothy J. Stalker
4. Platelet priming Paolo Gresele, Emanuela Dalcinelli and Stafania Momi
5. Platelets and coagulation José A. López and Ian del Conde
6. Vessel-wall-derived substances affecting platelets Azad Raiesdana and Joseph Loscalzo
7. Platelet-Leukocyte-Endothelial cross talk Kevin J. Croce, Masashi Sakuma and Daniel I. Simon
8. Laboratory investigation of platelets Eduard Shantsila, Timothy Watson and Gregory Y. H. Lip
9. Clinical approach to the bleeding patient Jos Vermylen and Kathelijne Peerlinck
10. Thrombocytopenia James Bussel and Andrea Primiani
11. Reactive and clonal thrombocytosis Ayalew Tefferi
12. Congenital disorders of platelet function Marco Cattaneo
13. Acquired disorders of platelet function Michael H. Kroll and Amy A. Hassan
14. Platelet transfusion therapy Sherrill J. Slichter and Ronald G. Strauss
15. Clinical approach to the patient with thrombosis Brian G. Choi and Valentin Fuster
16. Pathophysiology of arterial thrombosis Juan José Badimon, Borja Ibanez and Gemma Vilahur
17. Platelets and atherosclerosis Stephan Lindemann and Meinrad Gawaz
18. Platelets in other thrombotic conditions David L. Green, Peter W. Marks and Simon Karpatkin
19. Platelets in respiratory disorders and inflammatory conditions Paolo Gresele, Stefania Momi, Simon C. Pitchford and Clive P. Page
20. Platelet pharmacology Dermot Cox
21. Antiplatelet therapy versus other antithrombotic strategies Nicolai Mejevoi, Catalin Boiangiu and Marc Cohen
22. Laboratory monitoring of antiplatelet therapy Paul Harrison and David Keeling
23. Antiplatelet therapy in cardiology Pierluigi Tricoc and Robert A. Harrington
24. Antiplatelet therapy in cerebrovascular disease James Castle and Gregory W. Albers
25. Antiplatelet treatment in peripheral arterial disease Raymond Verhaeghe and Peter Verhamme
26. Antiplatelet treatment of venous thromboembolism Menno V. Huisman, Jaapjan D. Snoep, Jouke T. Tamsma and Marcel M. C. Hovens
Index.

Subject Areas: Haematology [MJF], Cardiovascular medicine [MJD]