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Plant Chemical Biology
Dominique Audenaert (Author), Paul Overvoorde (Author)
9780470946695, Wiley
Hardback, published 7 March 2014
320 pages
24.1 x 16.4 x 2.4 cm, 0.59 kg
Demonstrates how advances in plant chemical biology can translate to field applications With contributions from a team of leading researchers and pioneers in the field, this book explains how chemical biology is used as a tool to enhance our understanding of plant biology. Readers are introduced to a variety of chemical biology studies that have provided novel insights into plant physiology and plant cellular processes. Moreover, they will discover that chemical biology not only leads to a better understanding of the underlying mechanisms of plant biology, but also the development of practical applications. For example, the authors discuss small molecules that can be used to identify targets of herbicides and develop new herbicides and plant growth regulators. The book begins with a historical perspective on plant chemical biology. Next, the authors introduce the chemical biology toolbox needed to perform successful studies, with chapters covering: Based on the latest findings and extensively referenced, the book explores available compound collections, principles of assay design, and the use of new research tools for the development of new applications. Plant Chemical Biology is recommended for students and professionals in all facets of plant biology, including molecular biology, physiology, biochemistry, agriculture, horticulture, and agronomy. All readers will discover new approaches that can lead to the development of a healthier and more plentiful global food supply.
Preface vii Contributors ix Part one Introduction 1 1.1 From Herbal remedies to Cutting-edge science: a Historical Perspective of Plant Chemical biology 3 Part two sources of small molecules 19 2.1 Compound Collections 21 2.2 Combinatorial Chemistry library design 40 2.3 Natural Product-based libraries 64 Part three identification of new Chemical tools by High-throughPut screening 73 3.1 assay design for High-throughput screening 75 Part three use of CHemical biology to study Plant Physiology 93 4.1 Use of Chemical biology to understand auxin metabolism, signaling, and Polar transport 95 4.2 Brassinosteroids signaling and biosynthesis 128 4.3 Chemical genetic approaches on aba signal transduction 145 4.4 Jasmonic acid 160 4.5 Chemical genetics as a tool to study ethylene biology in Plants 184 Part five use of Chemical biology to study Plant Cellular Processes 203 5.1 The use of small molecules to dissect Cell wall biosynthesis and manipulate the Cortical Cytoskeleton 205 5.2 The use of Chemical biology to study Plant Cellular Processes: subcellular trafficking 218 Part six target identification 233 6.1 Target identification of biologically active small molecules 235 Part seven translation of Plant Chemical biology from the lab to the field 247 7.1 Prospects and Challenges for translating emerging insights in Plant Chemical biology into new agrochemicals 249 7.2 In Vitro Propagation 263 Index 289
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Subject Areas: Chemistry [PN]
