Pharmacological Treatment of Alzheimer's Disease
Molecular and Neurobiological Foundations

Jorge D. Brioni (Edited by), JD Brioni (Author), Michael W. Decker (Edited by)

9780471167587, Wiley

Hardback, published 21 March 1997

549 pages
24.2 x 16.5 x 3.3 cm, 0.992 kg

Geboten wird ein vollständiger, ausgewogener Überblick über die neuropharmakologischen Grundlagen von Therapeutika für die Alzheimer-Krankheit. Neueste Untersuchungen molekularer Strukturen und aktuelle klinische Daten werden mit der Verhaltens- und Erkenntnisforschung verknüpft und interpretiert.

I -
The Neurology of Cognition: Structure and Management of Multiple Memory Systems in Alzheimer's Disease

Interaction of Neuromodulatory Systems Regulating Memory Storage

Monoamine and Acetylcholine Influences on Higher Cognitive Functions in Nonhuman Primates with Relevance to the Treatment of Alzheimer's Disease

Cortical Acetylcholine and Attention: Neuropharmacological and Cognitive Principles Directing Treatment Strategies for Cognitive Disorders

Neuropsychological Features of Alzheimer's Disease

II -
Neuropathological Features of Alzheimer's Disease

Normal Brain Ageing and Alzheimer's Disease Pathology

Recent Developments in the Genetics of Alzheimer's Disease

Neurofibrillary Tangles in Alzheimer's Disease: Clinical and Pathological Implications

Amyloid Cytoxicity and Alzheimer's Disease: Roles of Membrane Oxidation and Perturbed Ion Homeostasis

The Role of Apolipoprotein E in Neurobiology and the Pathogenesis of Alzheimer's Disease

Animal Models Relevant to Alzheimer's Disease

III -
Alzheimer's Drug Discovery and Development: Alzheimer's Disease: An International Public Health Problem- Clinical Goals, Strategies and Outcomes

Use of CSF-based Markers in the Diagnosis of Alzheimer's Disease

Considerations for Clinical Trials in Alzheimer's Disease

Cholinesterase Inhibition in the Treatment of Alzheimer's Disease: Further Evaluation of the Clinical Effects of Tucrine

Development of Muscarinic Agonists for the Symptomatic Treatment of Alzheimer's Disease

Neuronal Nicotinic Receptors: Potential Treatment for Alzheimer's Disease with Novel Cholinergic Channel Activators

Neurotrophic Factors: Potential for Therapeutic Intervention in Alzheimer's Disease

A Fundamental Role for Estrogens in Cognition and Neuroprotection

Alzheimer's Disease: Prospects for Treatment in the Next Decade.

Subject Areas: Biology, life sciences [PS]